Methyl 5-chloro-1-(4-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate CAS 1018142-50-1
| CAS No. | 1018142-50-1 |
| Molecular Formula | C16H13ClFN3O2 |
| Molecular Weight | 333.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 5-chloro-1-(4-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate.
CATO supplies Methyl 5-chloro-1-(4-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018142-50-1), a certified reference material (molecular formula C16H13ClFN3O2, MW 333.74 g/mol) for analytical method development and quality control.
Based on its molecular formula C16H13ClFN3O2, Methyl 5-chloro-1-(4-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 333.74 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-chloro-1-(4-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13ClFN3O2 |
| Molecular Weight | 333.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- Methyl 5-chloro-1-(2-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011399-09-9)
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Recommended Standards
- ((5-Carboxy-2-chlorophenyl)sulfonyl)proline (CAS 1008580-51-5)
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- Penfluridol Impurity 3 (CAS CATO-C4X-35383)
- (2E)-N-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(pyrrolidin-1-yl)but-2-enamide (CAS 338397-34-5)
- (4-((Butoxycarbonyl)amino)phenyl)boronic acid (CAS 1259394-65-4)
- 7-Bromo-1,5-dihydropyrido[2,3-e][1,4]oxazepin-2(3H)-one (CAS 941603-99-2)
- N-methyl-1-(4-(2-methylpiperidin-1-yl)phenyl)methanamine (CAS 1095155-43-3)
- 6-Amino-1-butyl-5-{[(2-methoxyphenyl)methyl]amino}-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 571149-78-5)
- 3-(3-chlorophenyl)prop-2-ynenitrile (CAS 935528-57-7)
- 1,3,4-Triphenylazetidin-2-one (CAS 7477-20-5)
- Thieno[2,3-b]pyridine-2-carboxamide (CAS 1824270-94-1)
- 4-Methyl-5-(3-methyl-1,2,4-oxadiazol-5-yl)thiazol-2-amine (CAS 1119415-98-3)
- 180994-92-7 [3-(4-chlorophenyl)phenyl]boronic acid (CAS 180994-92-7)
- Proinsulin C-Peptide (55-89) (human) (CAS 11097-48-6)
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