1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-cyclopropanecarbonylpiperazine CAS 1024477-94-8
| CAS No. | 1024477-94-8 |
| Molecular Formula | C14H15ClF3N3O |
| Molecular Weight | 333.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-cyclopropanecarbonylpiperazine (CAS 1024477-94-8), a certified reference material (molecular formula C14H15ClF3N3O, MW 333.74 g/mol) for analytical method development and quality control.
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-cyclopropanecarbonylpiperazine (C14H15ClF3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H15ClF3N3O |
| Molecular Weight | 333.74 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
- (2E)-N-(3-Chloro-4-fluorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enamide (CAS 882081-97-2)
- (2E)-N-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(pyrrolidin-1-yl)but-2-enamide (CAS 338397-34-5)
- ((5-Carboxy-2-chlorophenyl)sulfonyl)proline (CAS 1008580-51-5)
- Penfluridol Impurity 3 (CAS CATO-C4X-35383)
- Methyl 3-(3-bromo-2-oxopyrrolidin-1-yl)propanoate (CAS 1343810-32-1)
- BMS 935177 (CAS 1231889-53-4)
- 2-Chloro-N-[3-cyano-4,5-dimethyl-1-(oxolan-2-ylmethyl)-1h-pyrrol-2-yl]acetamide (CAS 852400-21-6)
- 2-Hydroxy-6-(4-methylphenyl)pyridine-3-carbonitrile (CAS 37670-85-2)
- 2-Oxaspiro[3.5]nonan-7-ylmethanamine (CAS 1256667-38-5)
- (2e)-3-[5-chloro-3-methyl-1-(2-methylpropyl)-1h-pyrazol-4-yl]prop-2-enoic acid (CAS 1613051-23-2)
- 4-((cis-Hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methyl)-2-methylthiazole (CAS 1690132-71-8)
- 2-Methyl-n-(1,2,3,4-tetrahydroquinolin-5-yl)propanamide (CAS 1016526-76-3)
- 4-Chloro-1-methylquinolin-2(1H)-one (CAS 32262-17-2)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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