6-Chloro-4-(difluoromethyl)-2-ethyl-2h-pyrazolo[3,4-b]pyridine CAS 1018165-54-2
| CAS No. | 1018165-54-2 |
| Molecular Formula | C9H8ClF2N3 |
| Molecular Weight | 231.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 231.63 g/mol gives 6-Chloro-4-(difluoromethyl)-2-ethyl-2h-pyrazolo[3,4-b]pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Chloro-4-(difluoromethyl)-2-ethyl-2h-pyrazolo[3,4-b]pyridine (CAS 1018165-54-2) is a high-purity analytical reference standard with the molecular formula C9H8ClF2N3 and a molecular weight of 231.63 g/mol.
6-Chloro-4-(difluoromethyl)-2-ethyl-2h-pyrazolo[3,4-b]pyridine (C9H8ClF2N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-4-(difluoromethyl)-2-ethyl-2h-pyrazolo[3,4-b]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8ClF2N3 |
| Molecular Weight | 231.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 6-Chloro-4-(difluoromethyl)-2,3-dimethyl-2h-pyrazolo[3,4-b]pyridine (CAS 1018166-05-6)
- 3-chloro-6-(2-methoxyethoxy)pyridine-2-carboxylic acid (CAS 1020947-39-0)
- 2-CHloro-4-(2-methoxyethoxy)-1-nitrobenzene (CAS 147245-25-8)
- 1-Chloro-4-(2-methoxyethoxy)-2-nitrobenzene (CAS 1870242-16-2)
- 1-Chloro-2-ethoxy-3-methoxy-5-nitrobenzene (CAS 1881322-01-5)
- 1-chloro-3-(2-methoxyethoxy)-5-nitrobenzene (CAS 1881322-02-6)
- 1-Chloro-3-ethoxy-2-methoxy-5-nitrobenzene (CAS 1881332-18-8)
- 1-CHloro-2-(2-methoxyethoxy)-4-nitrobenzene (CAS 952490-76-5)
Recommended Standards
- 701-35-9 Trichloro-p-tolylsilane Benzene, 1-methyl-4-(trichlorosilyl)- Silane, trichloro(4-methylphenyl)- EINECS 211-854-0 Tolyltrichlorosilane p-Tolyltrichlorosilane (CAS 701-35-9)
- 5-(Chloromethyl)-2-(2,2,2-trifluoroethoxy)thiazole (CAS 1462380-20-6)
- 3-((3-Chloro-4-fluorophenyl)amino)-3-oxopropanoic acid (CAS 905810-26-6)
- 2-Amino-3-chloro-4,6-dimethoxybenzoic acid (CAS 1164251-94-8)
- 4-Bromo-3-methyl-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1536707-43-3)
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