Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) CAS 1335440-44-2
| CAS No. | 1335440-44-2 |
| Molecular Formula | C35H63N3O13 |
| Molecular Weight | 733.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2), a pharmacopoeial impurity reference standard (molecular formula C35H63N3O13, MW 733.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (C35H63N3O13) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 733.89 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C35H63N3O13 |
| Molecular Weight | 733.89 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Semaglutide Standards
- Semaglutide Impurity 146 (CAS 2645421-68-5)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
- Semaglutide Impurity 130 (CAS 1188328-40-6)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
- Semaglutide impurity 277 (CAS CATO-C4X-2226277)
- Semaglutide impurity 31 (CAS CATO-C4X-222631)
Recommended Standards
- Piperacillin Impurity 50 (CAS CATO-C4X-173250)
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Why CATO?
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