3-[5-(furan-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid CAS 1018166-13-6
| CAS No. | 1018166-13-6 |
| Molecular Formula | C13H9F3N4O3 |
| Molecular Weight | 326.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-[5-(furan-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1018166-13-6), molecular formula C13H9F3N4O3 and molecular weight 326.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-[5-(furan-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (C13H9F3N4O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-[5-(furan-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9F3N4O3 |
| Molecular Weight | 326.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related furan Standards
- 4-(Furan-2-ylmethyl)-1,5-dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid (CAS 847744-17-6)
- 7-(Furan-2-yl)-2-[(3,4,4-trifluorobut-3-en-1-yl)sulfanyl]-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 338777-08-5)
- 2-(4-(Furan-2-carbonyl)piperazin-1-yl)-5-nitrobenzonitrile (CAS 849516-63-8)
- (5-(Furan-2-yl)isoxazol-3-yl)methyl benzo[d]thiazole-2-carboxylate (CAS 1207048-59-6)
- 1-{[2-(Furan-2-yl)imidazo[1,2-a]pyrimidin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 904817-23-8)
- 4-(Furan-2-yl)-2-phenyl-5-[(Z)-2-phenyldiazen-1-yl]pyrimidine (CAS 339279-64-0)
- N-(2-(6-(Furan-2-yl)-1H-imidazo[1,2-b]pyrazol-1-yl)ethyl)thiophene-3-carboxamide (CAS 1795297-49-2)
- 3-(Furan-2-yl)-N-(4-(thiazol-2-yloxy)benzyl)acrylamide (CAS 2035007-02-2)
Recommended Standards
- Diniconazole (CAS 83657-24-3)
- N-Boc-1-(4-bromophenyl)cyclobutanamine (CAS 1032350-06-3)
- Brimonidine Impurity 17 (CAS 134892-47-0)
- tert-Butyl 8-bromo-4,5-dihydro-1H-benzo[c]azepine-2(3H)-carboxylate (CAS 1034573-54-0)
- Glyphosate Isopropylamine Salt (CAS 38641-94-0)
- 8-Fluorospiro[chromane-3,4'-piperidine] hydrochloride (CAS 909035-76-3)
- 2-Hydroxy-3,6-dimethylbenzaldehyde (CAS 1666-04-2)
- 5-Cyclohexyl-2-furancarboxylic acid (CAS 14174-52-8)
- Methyl 5-bromo-2-methyl-1H-indole-3-carboxylate (CAS 1225382-91-1)
- 2,2-Dimethyltetrahydropyran-4-one (CAS 1194-16-7)
- 2-((1-Benzylpiperidin-4-yl)oxy)acetic acid (CAS 751430-77-0)
- N-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)propan-1-amine (CAS 2377609-37-3)
- Methyl (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-(methylsulfanyl)propanoate (CAS 82835-08-3)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
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