Brimonidine Impurity 17 CAS 134892-47-0

Description

Compared with other compounds in its class, the molecular weight of 326.22 g/mol gives Brimonidine Impurity 17 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Brimonidine Impurity 17 (CAS 134892-47-0) is a certified pharmaceutical impurity reference standard with the molecular formula C11H12BrN5S and a molecular weight of 326.22 g/mol.

The molecular framework of Brimonidine Impurity 17 (C11H12BrN5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com