Ethyl 2-(imidazo[1,2-a]pyridin-3-yl)acetate CAS 101820-69-3
| CAS No. | 101820-69-3 |
| Molecular Formula | C11H12N2O2 |
| Molecular Weight | 204.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 2-(imidazo[1,2-a]pyridin-3-yl)acetate (CAS 101820-69-3) is a high-purity analytical reference standard with the molecular formula C11H12N2O2 and a molecular weight of 204.23 g/mol.
The molecular framework of Ethyl 2-(imidazo[1,2-a]pyridin-3-yl)acetate (C11H12N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2-(imidazo[1,2-a]pyridin-3-yl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12N2O2 |
| Molecular Weight | 204.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 2-(Imidazo[1,2-a]pyridin-2-yl)butanoic acid (CAS 1120249-23-1)
- 3-(Imidazo[1,2-a]pyridin-2-yl)-2-methylpropanoic acid (CAS 1539134-80-9)
- Methyl 3-imidazo[1,2-a]pyridin-2-ylpropanoate hydrobromide (CAS 332403-00-6)
- 1-(1H-imidazo[4,5-b]pyridin-2-yl)-3-methylbutan-1-amine (CAS 1247782-10-0)
- 2-(Imidazo[1,2-a]pyrimidin-2-yl)butanoic acid (CAS 1119410-17-1)
- Methyl 3-(imidazo[1,2-a]pyrimidin-2-yl)propanoate (CAS 1824097-15-5)
- Imidazo[1,2-a]pyrazine-3-carboxylic acid, 8-methyl-, ethyl ester (CAS 1956354-81-6)
- Ethyl 2-(imidazo[1,2-a]pyrazin-2-yl)acetate (CAS 77112-50-6)
Recommended Standards
- Minodronic Impurity 28 (CAS CATO-C4X-124128)
- Levosimendan Impurity 37 (CAS 103416-88-2)
- Minodronic Impurity 1 (CAS 21755-34-0)
- Levosimendan Impurity 39 (CAS 134678-48-1)
- (1S,4s)-1,4-bis(4-bromophenyl)-1,4-bis(methoxymethoxy)cyclohexane (CAS 2177264-24-1)
- 2-Acetoxy-2,4-difluorobenzophenone (CAS 890098-66-5)
- N-(3,4-Dimethoxyphenyl)tetrahydrofuran-2-carboxamide (CAS 774589-85-4)
- Ethyl 3-[4-(Hydroxymethyl)phenyl]propionate (CAS 107859-98-3)
- 6-Cyano-3-cyclopropoxypyridine-2-sulfonamide (CAS 1243367-85-2)
- 1-((Benzyloxy)methyl)-3-bromobenzene (CAS 3395-75-3)
- 2,4-Difluoro-5-methyl-3-(2-methylpropoxy)phenol (CAS 1881329-28-7)
- 1-Ethyl-3-(3-fluorophenyl)piperazine (CAS 1248908-22-6)
- test (CAS CATO-test17)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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