Levosimendan Impurity 37 CAS 103416-88-2
| CAS No. | 103416-88-2 |
| Molecular Formula | C11H12N2O2 |
| Molecular Weight | 204.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Levosimendan Impurity 37 (CAS 103416-88-2), a pharmacopoeial impurity reference standard (molecular formula C11H12N2O2, MW 204.23 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Levosimendan Impurity 37 (C11H12N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Levosimendan Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12N2O2 |
| Molecular Weight | 204.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Levosimendan Standards
- Levosimendan Impurity 39 (CAS 134678-48-1)
- Levosimendan Impurity 7 (CAS 134678-47-0)
- Levosimendan Impurity 11 (CAS 101328-84-1)
- Levosimendan Impurity 2 (CAS 101328-85-2)
- Levosimendan Impurity 3 (CAS 36725-28-7)
- Levosimendan impurity 71 (CAS CATO-C4X-130871)
- Levosimendan impurity 72 (CAS CATO-C4X-130872)
- Levosimendan Impurity 4 (CAS 42075-29-6)
Recommended Standards
- Ethyl 2-(imidazo[1,2-a]pyridin-3-yl)acetate (CAS 101820-69-3)
- Minodronic Impurity 28 (CAS CATO-C4X-124128)
- Minodronic Impurity 1 (CAS 21755-34-0)
- Raltitrexed Impurity 17 (CAS CATO-C4X-138617)
- Dabrafenib Impurity 12 (CAS CATO-C4X-303312)
- Topiroxostat Impurity 19 (CAS 38634-05-8)
- Methylaminolevulinate EP Impurity D (CAS 77479-02-8)
- methyl 4-(bromomethyl)-2-methoxybenzoate (CAS 74733-27-0)
- (S)-2-Amino-2-(3-(methoxymethyl)phenyl)ethanol hydrochloride (CAS 2061996-45-8)
- 2-Methy-4-Thioisonicotinicamide (CAS 3390-77-0)
- 7-Bromo-5-(bromomethyl)-2,3-dimethoxyquinoxaline (CAS 187479-70-5)
- (3-Aminobenzofuran-2-yl)(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanone (CAS 187154-67-2)
- 8-(Dibenzylamino)-1,4-dioxaspiro[4.5]decane (CAS 168893-04-7)
- (Asp28)-Exenatide trifluoroacetate salt (CAS 1678417-24-7)
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