Butenafine Impurity 4 CAS 101827-53-6
| CAS No. | 101827-53-6 |
| Molecular Formula | C23H27N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 353.93 g/mol gives Butenafine Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Butenafine Impurity 4 (CAS 101827-53-6) is a certified pharmaceutical impurity reference standard with the molecular formula C23H27NHCl and a molecular weight of 353.93 g/mol.
Structurally, Butenafine Impurity 4 (C23H27NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 353.93 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Butenafine Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27N HCl |
| Molecular Weight | 353.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Butenafine Standards
- Butenafine Hydrochloride (CAS 101827-46-7)
- Butenafine Impurity 5 (CAS 101828-08-4)
- Butenafine (CAS 101828-21-1)
- Butenafine Impurity 8 (CAS 110931-65-2)
- Butenafine Impurity 11 (CAS 110951-99-0)
- Butenafine Impurity 3 (CAS 122152-13-0)
- Butenafine Impurity 14 (CAS 124830-38-2)
- Butenafine Impurity 31 (CAS 141788-33-2)
Recommended Standards
- Mivacurium chloride Impurity 56 (CAS CATO-C4X-137556)
- Minocycline Impurity 64 (CAS CATO-C4X-169964)
- Relebactam Impurity 32 (CAS CATO-C4X-214432)
- 2-((4-Bromo-5-(dimethylamino)furan-2-yl)methylene)-N-phenylhydrazinecarbothioamide (CAS 469885-16-3)
- 2-(4-Fluorophenyl)-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 861210-34-6)
- 5-Hydroxybenzo[d][1,3]oxathiol-2-one (CAS 7735-56-0)
- 2-methoxy-2-(3-methoxyphenyl)ethan-1-amine hydrochloride (CAS 23582-54-9)
- 1-(4-Methoxyphenyl)-1,2-diphenylbutan- 1-ol (CAS 650624-50-3)
- Quinoline-6-sulfonamide (CAS 89770-31-0)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
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