tert-Butyl (4-chloro-3-fluoro-2-iodophenyl)carbamate CAS 1018450-35-5
| CAS No. | 1018450-35-5 |
| Molecular Formula | C11H12ClFINO2 |
| Molecular Weight | 371.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 371.57 g/mol gives tert-Butyl (4-chloro-3-fluoro-2-iodophenyl)carbamate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
tert-Butyl (4-chloro-3-fluoro-2-iodophenyl)carbamate (CAS 1018450-35-5) is a high-purity analytical reference standard with the molecular formula C11H12ClFINO2 and a molecular weight of 371.57 g/mol.
The molecular framework of tert-Butyl (4-chloro-3-fluoro-2-iodophenyl)carbamate (C11H12ClFINO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures tert-Butyl (4-chloro-3-fluoro-2-iodophenyl)carbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12ClFINO2 |
| Molecular Weight | 371.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Finasteride Impurity 18 (CAS 131267-80-6)
- tert-Butyl (2-chloro-4-fluoro-3-iodophenyl)carbamate (CAS 2573784-38-8)
- Finasteride Impurity 13 (CAS CATO-C4X-164513)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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