Finasteride Impurity 18 CAS 131267-80-6
| CAS No. | 131267-80-6 |
| Molecular Formula | C24H37NO2 |
| Molecular Weight | 371.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 371.56 g/mol gives Finasteride Impurity 18 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Finasteride Impurity 18 (CAS 131267-80-6), a pharmacopoeial impurity reference standard (molecular formula C24H37NO2, MW 371.56 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Finasteride Impurity 18 (C24H37NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H37NO2 |
| Molecular Weight | 371.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 1 |
Related Finasteride Standards
- Finasteride Impurity 13 (CAS CATO-C4X-164513)
- Finasteride (CAS 98319-26-7)
- Finasteride Impurity 11 (CAS CATO-C4X-164511)
- Finasteride Impurity 15 (CAS 140375-21-9)
- Finasteride Impurity 19 (CAS 166896-74-8)
- 5-Beta-Finasteride (CAS 140375-22-0)
- Finasteride Impurity 55 (CAS CATO-C4X-164555)
- Finasteride Impurity 27 (CAS 1329611-51-9)
Recommended Standards
- tert-Butyl (4-chloro-3-fluoro-2-iodophenyl)carbamate (CAS 1018450-35-5)
- 1,4-dimethyl-2-(prop-2-en-1-yloxy)benzene 4236-73-1 KST-1B4204 (CAS 4236-73-1)
- tert-Butyl (2-chloro-4-fluoro-3-iodophenyl)carbamate (CAS 2573784-38-8)
- Repaglinide Impurity IV (CAS 646054-50-4)
- Carbocisteine Impurity 26 (CAS CATO-C4X-201026)
- Amifostine Impurity 6 (CAS 5458-99-1)
- Ceftriaxone Impurity 34 (CAS 1637561-91-1)
- (E)-2-((2-fluorobenzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-30-6)
- 3-(3-Methylphenoxy)propan-1-amine, HCl (CAS 1052077-26-5)
- 1-(3-Fluoro-5-(isopentyloxy)phenyl)ethanol (CAS 1443329-60-9)
- Afatinib Impurity 50 (CAS 2413212-25-4)
- 4-Bromo-2-(3,3-difluoropyrrolidin-1-yl)pyridine (CAS 1774897-00-5)
- (1-Methyl-1,2-ethanediyl)bis-Carbamodithioic Acid Dimethyl Ester (CAS 80555-60-8)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com