3-Chloro-5-(methylsulfonyl)-1,2,4-thiadiazole CAS 10191-91-0
| CAS No. | 10191-91-0 |
| Molecular Formula | C3H3ClN2O2S2 |
| Molecular Weight | 198.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Chloro-5-(methylsulfonyl)-1,2,4-thiadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Chloro-5-(methylsulfonyl)-1,2,4-thiadiazole (CAS 10191-91-0) is a high-purity analytical reference standard with the molecular formula C3H3ClN2O2S2 and a molecular weight of 198.65 g/mol.
The molecular framework of 3-Chloro-5-(methylsulfonyl)-1,2,4-thiadiazole (C3H3ClN2O2S2) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C3H3ClN2O2S2 |
| Molecular Weight | 198.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Chloro Standards
- 6-Chloro-4-(isopropylamino)nicotinaldehyde (CAS 1012880-02-2)
- 2-Chloro-6-(cyclopentyloxy)pyrazine (CAS 1016697-18-9)
- 5-Chloro-6-methyl-3-(pyrrolidin-1-yl)-1,2,4-triazine (CAS 1023818-03-2)
- Methyl 2-(5-chloro-2-methylphenyl)acetate (CAS 1076191-96-2)
- Methyl (2-chloro-6-methylphenyl)acetate (CAS 1076192-08-9)
- 3-(4-Chloro-3-methylphenyl)propanoic acid (CAS 1086386-05-1)
- 2-Chloro-N-ethyl-N-methylnicotinamide (CAS 112006-59-4)
- 4-chloro-6-cyclopentyl-1,3,5-triazin-2-amine (CAS 1139245-04-7)
Recommended Standards
- 4-Amino-3-chloro-N,N-dimethylbenzamide (CAS 1019018-13-3)
- Methyl 2-(3-chlorophenyl)propanoate (CAS 103040-42-2)
- Methyl 3-(3-chlorophenyl)propanoate (CAS 103040-43-3)
- 3-(4-Chlorophenyl)-2-methylpropanoic acid (CAS 1012-17-5)
- 68578-79-0 4,4'-(1,2-Diphenylethene-1,2-diyl)diphenol DTXSID50712287 (CAS 68578-79-0)
- 1-Methyl-3,3-diphenyl-2,3-dihydro-1H-indol-2-one (CAS 22136-54-5)
- 2-(2,6-Dichloro-4-(trifluoromethyl)phenyl)-4-methylphthalazin-1(2H)-one (CAS 672951-12-1)
- 3-Hydroxy-2,7-naphthalenedisulfonic Acid Sodium Salt > 90% (CAS 15883-57-5)
- 4-Imino-6,7-dimethoxy-3-(3-methoxypropyl)-1,2,3,4-tetrahydroquinazoline-2-thione (CAS 477848-74-1)
- 5-((Trifluoromethyl)sulfonyl)furan-2-carboxylic acid (CAS 1342010-68-7)
- 2-Methoxy-2-methyl-3-phenylpropan-1-amine (CAS 1469015-78-8)
- (5-Bromo-2-(trifluoromethyl)phenyl)methanol (CAS 1214349-54-8)
- 1-BROMO-3-(1-METHYLETHYL)BENZENE 1-BROMO-3-(PROPAN-2-YL)BENZENE 1-BROMO-3-ISOPROPYLBENZENE 3-BROMOISOPROPYLBENZENE 3-Isopropylbromobenzene 5433-01-2 AS05658 (CAS 5433-01-2)
- Glucagon receptor antagonist I (CAS 438618-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com