5-Chloro-6-[(1-methyl-1h-imidazol-2-yl)sulfanyl]pyridine-3-carboxylic acid CAS 1019324-90-3
| CAS No. | 1019324-90-3 |
| Molecular Formula | C10H8ClN3O2S |
| Molecular Weight | 269.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-6-[(1-methyl-1h-imidazol-2-yl)sulfanyl]pyridine-3-carboxylic acid.
5-Chloro-6-[(1-methyl-1h-imidazol-2-yl)sulfanyl]pyridine-3-carboxylic acid (CAS 1019324-90-3), molecular formula C10H8ClN3O2S and molecular weight 269.71 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-6-[(1-methyl-1h-imidazol-2-yl)sulfanyl]pyridine-3-carboxylic acid (C10H8ClN3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN3O2S |
| Molecular Weight | 269.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 5-Formylamino-naphthalene-1-sulfonyl chloride 5-formylaminonaphthalene-1-sulfonyl chloride 680618-20-6 (CAS 680618-20-6)
- tert-butyl 2-chloro-4-(difluoromethyl)-1,3-thiazole-5-carboxylate (CAS 2060024-91-9)
- (2-[(5-Chloropyridin-2-yl)amino]-1,3-thiazol-4-yl)acetic acid (CAS 1176721-33-7)
- Methyl 3-[(6-chloropyridin-2-yl)oxy]thiophene-2-carboxylate (CAS 338756-33-5)
- 2-Chloro-4-(1-ethoxy-vinyl)thieno[3,2-d]pyrimidine (CAS 1135299-22-7)
- 3-(2,5-Dimethylphenyl)butan-1-amine (CAS 65410-58-4)
- 3,5-Dimethyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole (CAS 1154361-20-2)
- 4-(2-Amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol (CAS 24085-19-6)
- 2-Chloro-4-fluoro-N-(piperidin-3-yl)benzamide hydrochloride (CAS 1833471-56-9)
- trans-Dichlorobis(4-chloropyridine)platinum (CAS 24476-74-2)
- 2-Azido-3-methylimidazo[4,5-f]quinoline (CAS 115397-29-0)
- 3470-53-9 6-Amino-1,2,3,4-tetrahydronaphthalen-1-one 6-Amino-1-tetralone 6-amino-3,4-dihydro-2H-naphthalen-1-one (CAS 3470-53-9)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
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