(2-[(5-Chloropyridin-2-yl)amino]-1,3-thiazol-4-yl)acetic acid CAS 1176721-33-7
| CAS No. | 1176721-33-7 |
| Molecular Formula | C10H8ClN3O2S |
| Molecular Weight | 269.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2-[(5-Chloropyridin-2-yl)amino]-1,3-thiazol-4-yl)acetic acid (CAS 1176721-33-7), molecular formula C10H8ClN3O2S and molecular weight 269.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-[(5-Chloropyridin-2-yl)amino]-1,3-thiazol-4-yl)acetic acid (C10H8ClN3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures (2-[(5-Chloropyridin-2-yl)amino]-1,3-thiazol-4-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN3O2S |
| Molecular Weight | 269.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Ethyl 2-chloro-4-(pyrazin-2-yl)thiazole-5-carboxylate (CAS 1093114-57-8)
- (3-Chloro-benzyl)-(2-trifluoromethylsulfanylethyl)-amine (CAS 1208079-59-7)
- 5-Chloro-6-[(1-methyl-1h-imidazol-2-yl)sulfanyl]pyridine-3-carboxylic acid (CAS 1019324-90-3)
- 3-Chloro-4-hydroxy-N-(3-methyl-1,2,4-thiadiazol-5-yl)benzamide (CAS 1384673-05-5)
- Sodium phenylmethanesulfinate (CAS 51793-64-7)
- 1-nitroso-3-(1-nitrosopiperidin-2-yl)-1H-indole (CAS 857775-93-0)
- Secnidazole-D6 (CAS 1346603-27-7)
- N-(6-Bromo-5-fluoropyridin-3-yl)acetamide (CAS 2750509-91-0)
- Nebivolol Impurity 31（RR,SR）or（RS,RR） (CAS 119365-26-3)
- 4-Bromo-5-chloro-6-methylnicotinic acid (CAS 1423025-36-8)
- 4-Amino-N,1-dimethyl-N-phenyl-1H-pyrazole-3-carboxamide (CAS 1489360-97-5)
- 2-Picoline-3-ethanol (CAS 1977-05-5)
- 1-(3-Methyl-4-propoxyphenyl)ethan-1-one (CAS 59865-30-4)
- Exenatide (CAS 141758-74-9（free base）)
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