Ethyl 4-chloro-6-fluoro-8-methylquinoline-3-carboxylate CAS 1019355-72-6
| CAS No. | 1019355-72-6 |
| Molecular Formula | C13H11ClFNO2 |
| Molecular Weight | 267.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 4-chloro-6-fluoro-8-methylquinoline-3-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 4-chloro-6-fluoro-8-methylquinoline-3-carboxylate (CAS 1019355-72-6) is a high-purity analytical reference standard with the molecular formula C13H11ClFNO2 and a molecular weight of 267.68 g/mol.
Based on its molecular formula C13H11ClFNO2, Ethyl 4-chloro-6-fluoro-8-methylquinoline-3-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 267.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 4-chloro-6-fluoro-8-methylquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11ClFNO2 |
| Molecular Weight | 267.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 3-(4-Chloro-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propan-1-amine (CAS 1006454-49-4)
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- 3-Acetyl-7-chloro-1-ethyl-6-fluoroquinolin-4(1H)-one (CAS 105892-51-1)
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Recommended Standards
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- 3-Phenylpropyl (3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)carbamate (CAS 478249-69-3)
- Heptan-2-yl 2-chloroacetate (CAS 383412-05-3)
- 1-(4-Bromobenzyl)indolin-2-one (CAS 1226397-96-1)
- N-ethyl-N-(4-iodobenzyl)ethanamine (CAS 914636-94-5)
- 2-Amino-4-phenylbutan-1-ol (CAS 160886-95-3)
- (5-Bromo-2-fluoro-4-methylphenyl)(methyl)sulfane (CAS 2379322-83-3)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
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