7-Chloro-[1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one CAS 1020037-45-9
| CAS No. | 1020037-45-9 |
| Molecular Formula | C5H3ClN4O |
| Molecular Weight | 170.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Chloro-[1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one (C5H3ClN4O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
7-Chloro-[1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one (CAS 1020037-45-9), molecular formula C5H3ClN4O and molecular weight 170.56 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Chloro-[1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3ClN4O |
| Molecular Weight | 170.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-1H-purin-2(3H)-one (CAS 1146697-79-1)
- 2-Chloro-6-hydroxypurine (CAS 13368-14-4)
- 6-Chloro-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one (CAS 1378849-61-6)
- 6-Chloro-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one (CAS 1384265-61-5)
- 5-Chloro-[1,2,4]triazolo[4,3-a]pyrazin-3(2H)-one (CAS 1421601-17-3)
- 3-Chloro-5-cyano-1H-pyrazole-4-carboxamide (CAS 90801-56-2)
- 5-Chloro-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-one (CAS 33386-23-1)
- 6-Chloro-7H-purin-8(9H)-one (CAS 37527-48-3)
Recommended Standards
- Gimeracil impurity 12 (CAS 149143-68-0)
- Imidazo[1,2-b]isoxazole-2-carbonyl chloride (CAS 914637-84-6)
- 6-Chlorooxazolo[4,5-β]pyridin-2(3H)-one (CAS 35570-68-4)
- 6-Chloro-2-hydroxy-4-oxo-1,4-dihydropyridine-3-carbonitrile (CAS 19867-18-6)
- (4-Chloro-3-methoxyphenyl)methanamine hydrochloride (CAS 169045-11-8)
- 1-butyl-3-methylpyridin-1-ium tetrafluoroborate (CAS 597581-48-1)
- tert-butyl 5-bromo-3,6-dihydro-2H-pyridine-1-carboxylate (CAS 1415841-82-5)
- methyl 6-(4-fluorophenyl)-6-oxohexanoate (CAS 342636-35-5)
- 4,4,4-Trifluoro-butane-1-sulfonyl chloride (CAS 212190-25-5)
- Hydrochlorothiazide-d2 (CAS 1219798-89-6)
- 2-(2-Chlorophenoxy)-N-ethyl-N-(2-hydroxyethyl)acetamide (CAS 1183201-91-3)
- P-Phos RuCl (p-cymene)]Cl (CAS 942441-13-6)
- 4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1072811-23-4)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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