Anagrelide Impurity 2 CAS 1020243-02-0
| CAS No. | 1020243-02-0 |
| Molecular Formula | C7H4Cl2N2 |
| Molecular Weight | 187.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Anagrelide Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Anagrelide Impurity 2 (CAS 1020243-02-0) is a certified pharmaceutical impurity reference standard with the molecular formula C7H4Cl2N2 and a molecular weight of 187.03 g/mol.
Structurally, Anagrelide Impurity 2 (C7H4Cl2N2) contains a nitrile group, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 187.03 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl2N2 |
| Molecular Weight | 187.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Anagrelide Standards
- Anagrelide Impurity 24 (CAS 147249-41-0)
- Anagrelide Impurity 10 (CAS 147249-42-1)
- Anagrelide Impurity 38 (CAS CATO-C4X-224038)
- Anagrelide Impurity 37 (CAS CATO-C4X-224037)
- Anagrelide Impurity 13 (CAS CATO-C4X-224013)
- Anagrelide Impurity 9 (CAS 28165-60-8)
- Anagrelide Impurity 26 (CAS 444904-63-6)
- Anagrelide Impurity 20 (CAS 2112-22-3)
Recommended Standards
- 4-Bromoanisole (CAS 104-92-7)
- 3-Bromoanisole (CAS 2398-37-0)
- 2-Bromoanisole (CAS 578-57-4)
- (4-Bromophenyl)methanol (CAS 873-75-6)
- Pheniramine Impurity 2 (CAS 67168-93-8)
- Idebenone Impurity 3 (CAS CATO-C4X-30163)
- Apixaban Impurity 150 (CAS CATO-C4X-1088150)
- 4-Oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 31601-88-4)
- 1-Benzyl-4-(4-fluorophenoxy)phthalazine (CAS 338404-25-4)
- 6-(3-Bromophenyl)pyrimidine-4-carboxylic acid (CAS 1426411-56-4)
- Ethyl (2,5-dioxopyrrolidin-3-yl)glycinate (CAS 1218353-25-3)
- 2-Methyl-N-(2,2,2-trichloroacetyl)alanine (CAS 95038-13-4)
- 2-Chloro-4-methylnicotinamide (CAS 152362-01-1)
- Tirzepatide Impurity 24 X TFA Salt (CAS CATO-C4X-324024)
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