Anagrelide Impurity 26 CAS 444904-63-6
| CAS No. | 444904-63-6 |
| Molecular Formula | C8H7Cl2N3 |
| Molecular Weight | 216.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Anagrelide Impurity 26.
CATO supplies Anagrelide Impurity 26 (CAS 444904-63-6), a pharmacopoeial impurity reference standard (molecular formula C8H7Cl2N3, MW 216.07 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Anagrelide Impurity 26 (C8H7Cl2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Anagrelide Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7Cl2N3 |
| Molecular Weight | 216.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Anagrelide Standards
- Anagrelide Impurity 20 (CAS 2112-22-3)
- Anagrelide Impurity 1 (CAS 70380-49-3)
- Anagrelide Impurity 13 (CAS CATO-C4X-224013)
- Anagrelide Impurity 9 (CAS 28165-60-8)
- Anagrelide Impurity 21 (CAS 17700-09-3)
- Anagrelide Impurity 22 (CAS 20098-48-0)
- Anagrelide Impurity 37 (CAS CATO-C4X-224037)
- Anagrelide Impurity 38 (CAS CATO-C4X-224038)
Recommended Standards
- 5,7-Dichloro-6-ethylpyrazolo[1,5-a]pyrimidine (CAS 754211-04-6)
- 3-Bromo-4-ethoxyaniline (CAS 101251-12-1)
- 5,6-dichloro-1-methyl-1H-1,3-benzodiazol-2-amine (CAS 30486-79-4)
- 3-(3-Bromopropoxy)pyridine (CAS 1024602-98-9)
- Tobramycin Impurity 3 (CAS CATO-C4X-22003)
- Polaprezinc impurity 27 (CAS CATO-C4X-182127)
- Mianserin Impurity 74 (CAS CATO-C4X-136974)
- 1-[(2-Chlorophenyl)methyl]-6-(3,4-dichlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 252059-61-3)
- 2-Amino-N-(4-methoxyphenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide (CAS 774575-35-8)
- (5-Methyl-2,4-dioxo-1,3-thiazolidin-5-yl)acetic acid (CAS 496020-58-7)
- 4-Chloro-7-nitro-2,1,3-benzothiadiazole (CAS 2207-29-6)
- (1-Benzyl-4-fluoropiperidin-3-yl)methanol (CAS 1356338-80-1)
- 2-(Difluoromethyl)-5-hydroxy-4-nitropyridine-3-carbonyl chloride (CAS 1807002-89-6)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com