| CAS No. | 1020745-85-0 |
| Molecular Formula | C6H5BrFNS |
| Molecular Weight | 222.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 222.08 g/mol gives 2-Amino-5-bromo-3-fluorobenzene-1-thiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-5-bromo-3-fluorobenzene-1-thiol (CAS 1020745-85-0) is a high-purity analytical reference standard with the molecular formula C6H5BrFNS and a molecular weight of 222.08 g/mol.
2-Amino-5-bromo-3-fluorobenzene-1-thiol (C6H5BrFNS) contains a nitrile group, sulfur-containing functionality, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-5-bromo-3-fluorobenzene-1-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C6H5BrFNS |
| Molecular Weight | 222.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |