1H-Indole-2, 5,7-dichloro- 5,3-dione 5,7-Dichloroisatin 6374-92-1 Indole-2, 5,7-dichloro- Isatin,7-dichloro- MLS002639083 NSC-26045 NSC26045 CAS 6374-92-1

Purity 97%+In StockPharmaceutical Standards
CAS No.6374-92-1
Molecular FormulaC8H9Cl2NO2
Molecular Weight222.07 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1H-Indole-2, 5,7-dichloro-
5,3-dione
5,7-Dichloroisatin
6374-92-1
Indole-2, 5,7-dichloro-
Isatin,7-dichloro-
MLS002639083
NSC-26045
NSC26045 CAS 6374-92-1 chemical structure

Description

The occurrence of 1H-Indole-2, 5,7-dichloro- 5,3-dione 5,7-Dichloroisatin 6374-92-1 Indole-2, 5,7-dichloro- Isatin,7-dichloro- MLS002639083 NSC-26045 NSC26045 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1H-Indole-2, 5,7-dichloro- 5,3-dione 5,7-Dichloroisatin 6374-92-1 Indole-2, 5,7-dichloro- Isatin,7-dichloro- MLS002639083 NSC-26045 NSC26045 (CAS 6374-92-1), molecular formula C8H9Cl2NO2 and molecular weight 222.07 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1H-Indole-2, 5,7-dichloro- 5,3-dione 5,7-Dichloroisatin 6374-92-1 Indole-2, 5,7-dichloro- Isatin,7-dichloro- MLS002639083 NSC-26045 NSC26045 (C8H9Cl2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H9Cl2NO2
Molecular Weight222.07 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Halogen ContentCl-containing
Nitrogen Atoms1

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