N-(4-(3-((2,6-Difluorobenzyl)amino)-3-oxopropyl)thiazol-2-yl)benzamide CAS 1021256-75-6
| CAS No. | 1021256-75-6 |
| Molecular Formula | C20H17F2N3O2S |
| Molecular Weight | 401.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-(3-((2,6-Difluorobenzyl)amino)-3-oxopropyl)thiazol-2-yl)benzamide (C20H17F2N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-(4-(3-((2,6-Difluorobenzyl)amino)-3-oxopropyl)thiazol-2-yl)benzamide (CAS 1021256-75-6), molecular formula C20H17F2N3O2S and molecular weight 401.43 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17F2N3O2S |
| Molecular Weight | 401.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- Methyl 2-({[1-(3,4-difluorobenzyl)-6-oxo-1,6-dihydro-3-pyridinyl]carbonyl}amino)benzenecarboxylate (CAS 242797-45-1)
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- 1-(3,4-Difluorobenzyl)-N-(3,4-dimethylphenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 242797-44-0)
- 2-((2,6-Difluorobenzyl)thio)-3-ethyl-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 578698-75-6)
- N-(3,4-difluorobenzyl)-6,7,8-trimethoxyquinazolin-4-amine (CAS 150450-17-2)
Recommended Standards
- methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011396-58-9)
- (4-(Morpholinosulfonyl)-2-nitrophenyl)-L-leucine (CAS 1030021-54-5)
- Dithiopyr (CAS 97886-45-8)
- 1142205-37-5 9343AC C21H24FN3O4 [{2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl}(4-methoxyphenyl)amino]acetic acid (CAS 1142205-37-5)
- (4-Ethyl-1,2,3-thiadiazol-5-yl)(3-(methylamino)piperidin-1-yl)methanone hydrochloride (CAS 1832768-16-7)
- 3-((4-Chloro-3-nitrophenyl)amino)-1-(3-nitrophenyl)propan-1-one (CAS 882748-65-4)
- (R)-N-(1-(4-formylphenyl)ethyl)methanesulfonamide (CAS 1448682-03-8)
- 4-Chloro-7-methylfuro[3,2-c]pyridine (CAS 117612-64-3)
- N,N-dimethyl-2-(4-nitrophenyl)ethan-1-amine hydrochloride (CAS 1803605-41-5)
- 4-Bromo-5-(bromomethyl)-2-methylthiazole (CAS 1799412-37-5)
- Tert-butyl (2,2-dimethylazetidin-3-yl)carbamate (CAS 2090335-49-0)
- 1-(4-Chlorobenzyl)cyclopropanamine (CAS 27018-60-6)
- 2-Hydroxy-6-isobutylpyrimidine-4-carboxylic acid hydrochloride (CAS 1401319-33-2)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
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