methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate CAS 1011396-58-9
| CAS No. | 1011396-58-9 |
| Molecular Formula | C24H20FN3O2 |
| Molecular Weight | 401.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011396-58-9), a certified reference material (molecular formula C24H20FN3O2, MW 401.43 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 401.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H20FN3O2 |
| Molecular Weight | 401.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related methyl Standards
- N-Cyclopropyl-2,4-difluoro-5-(((2-(pyridin-2-ylamino)thiazol-5-yl)methyl)amino)benzamide (CAS 639858-32-5)
- (1-((3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl)-4,4-dioxido-1H-benzo[e][1,3,4]thiadiazin-3-yl)(pyrrolidin-1-yl)methanone (CAS 1251698-42-6)
- 1-(2-((3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 1797181-12-4)
- (5-Cyclopropyl-isoxazol-4-yl)-(4-ethanesulfonyl-2,5-dimethyl-3-oxazol-2-yl-phenyl)-methanone (CAS 1231571-57-5)
- (5-Cyclopropyl-isoxazol-4-yl)-(3-ethanesulfonyl-2,5-dimethyl-4-oxazol-2-yl-phenyl)-methanone (CAS 1231596-90-9)
- 5-Cyclopropyl-2-(4-fluorophenyl)-N-methyl-6-(methylsulfonamido)benzofuran-3-carboxamide (CAS 691856-35-6)
- 2-(3-Cyclopropyl-4-(difluoromethyl)-6-(3,4-dimethoxyphenyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937607-35-7)
- Methyl 5-cyclopropyl-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxylate (CAS 1416438-14-6)
Recommended Standards
- Dithiopyr (CAS 97886-45-8)
- N-(4-(3-((2,6-Difluorobenzyl)amino)-3-oxopropyl)thiazol-2-yl)benzamide (CAS 1021256-75-6)
- (E)-Ceftizoxime Impurity 61 (CAS CATO-C4X-179361)
- (4-(Morpholinosulfonyl)-2-nitrophenyl)-L-leucine (CAS 1030021-54-5)
- Dipropyl 3,3'-thiodipropanoate (CAS 4275-35-8)
- 3-Ethoxy-4-(isopentyloxy)benzaldehyde (CAS 85259-29-6)
- 2-Amino-1-(5-bromothiophen-2-yl)propan-1-one (CAS 1216001-89-6)
- 4-Acetylpiperazin-2-one (CAS 17796-61-1)
- (2-Phenylquinolin-4-yl)methanol (CAS 29268-33-5)
- 2-(7-Cyano-1H-benzo[d]imidazol-1-yl)acetic acid (CAS 796972-98-0)
- 5-(Hydroxymethyl)-3-(trifluoromethyl)pyridin-2(1H)-one (CAS 1378689-13-4)
- (2-Amino-3-bromo-5-fluorophenyl)methanol (CAS 55414-45-4)
- 5-(Trifluoromethyl)pyridazine-3-sulfonamide (CAS 2005712-51-4)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
Why CATO?
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