[4-methyl-2-(trifluoromethyl)phenyl]boronic acid CAS 1021860-94-5
| CAS No. | 1021860-94-5 |
| Molecular Formula | C8H14BF3O2 |
| Molecular Weight | 210.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of [4-methyl-2-(trifluoromethyl)phenyl]boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies [4-methyl-2-(trifluoromethyl)phenyl]boronic acid (CAS 1021860-94-5), a certified reference material (molecular formula C8H14BF3O2, MW 210.00 g/mol) for analytical method development and quality control.
The molecular framework of [4-methyl-2-(trifluoromethyl)phenyl]boronic acid (C8H14BF3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14BF3O2 |
| Molecular Weight | 210.00 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.5 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related methyl Standards
- [3-methyl-4-(trifluoromethyl)phenyl]boronic acid (CAS 864759-67-1)
- 2,2-Bis(trifluoromethyl)-1,3-dioxolane (CAS 1765-26-0)
- 2,2-Bis(trifluoromethyl)propanoic acid (CAS 45048-36-0)
- Ethyl 3-(trifluoromethyl)-1,2,4-oxadiazole-5-carboxylate (CAS 1245643-72-4)
- 2-[5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]acetic acid (CAS 1339865-89-2)
- methyl 2-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]acetate (CAS 1803600-75-0)
- ethyl 5-(trifluoromethyl)-1,2,4-oxadiazole-3-carboxylate (CAS 914773-13-0)
- Ethyl 5-(trifluoromethyl)-1,3,4-oxadiazole-2-carboxylate (CAS 944903-98-4)
Recommended Standards
- Imidazo[1,2-a]quinoxaline (CAS 235-05-2)
- 4,4,5,5-Tetramethyl-2-(2,2,2-trifluoroethyl)-1,3,2-dioxaborolane (CAS 1450638-17-1)
- 4,6-Dichloro-2-fluoronicotinic acid (CAS 2518245-81-1)
- 3-Methoxy-4-methoxycarbonylbenzeneboronic acid, 97% (CAS 603122-41-4)
- Hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one hydrochloride (CAS 1628557-06-1)
- 2-(Chloromethyl)-3-(2-chlorophenyl)quinazolin-4(3H)-one (CAS 22312-83-0)
- (2Z)-2-(4-Chlorobenzenesulfonyl)-3-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)prop-2-enenitrile (CAS 1025270-09-0)
- 3-[(3,4-dimethoxyphenyl)amino]-2,3-dihydro-1lambda6-thiophene-1,1-dione (CAS 914217-77-9)
- 2-Chloro-3-methoxy-5-methylpyrazine (CAS 870543-99-0)
- Avibactam impurity 97 (CAS 2064219-26-5)
- 4,4-Difluorooctahydro-1H-isoindole hydrochloride (CAS 2411288-36-1)
- (S)-1-(5-Methylfuran-2-yl)propan-1-amine (CAS 473732-95-5)
- (3-(Pyridin-2-yl)phenyl)methanamine (CAS 859915-26-7)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
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