2-((4-Chlorophenyl)thio)-N-(7-oxo-5-phenyl-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)propanamide CAS 1022134-11-7
| CAS No. | 1022134-11-7 |
| Molecular Formula | C22H19ClN2O2S2 |
| Molecular Weight | 442.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((4-Chlorophenyl)thio)-N-(7-oxo-5-phenyl-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)propanamide.
2-((4-Chlorophenyl)thio)-N-(7-oxo-5-phenyl-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)propanamide (CAS 1022134-11-7), molecular formula C22H19ClN2O2S2 and molecular weight 442.98 g/mol, is a CATO reference standard with documented purity and traceability.
2-((4-Chlorophenyl)thio)-N-(7-oxo-5-phenyl-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)propanamide (C22H19ClN2O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((4-Chlorophenyl)thio)-N-(7-oxo-5-phenyl-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)propanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H19ClN2O2S2 |
| Molecular Weight | 442.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- (E)-{2-[(4-chlorophenyl)sulfanyl]-1-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}ethylidene}[(4-methylphenyl)methoxy]amine (CAS 866131-18-2)
- 2-[(4-Chlorophenyl)methanesulfonyl]-4-(2,3-dimethylphenoxy)-5,6,7,8-tetrahydroquinazoline (CAS 339019-19-1)
- 1-Benzyl-4-[3-(4-chlorophenyl)-5-(methylsulfanyl)thiophene-2-carbonyl]piperazine (CAS 477858-00-7)
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- 3-((4-Chlorophenyl)sulfonyl)-2-imino-10-methyl-1-propyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 573694-78-7)
- Methyl 5-((2-chlorophenyl)carbamoyl)-4-methyl-2-(3-methylbenzamido)thiophene-3-carboxylate (CAS 335407-75-5)
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Recommended Standards
- 2-((5-((4-Chlorophenoxy)methyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethan-1-one (CAS 483285-92-3)
- N-(4-chlorobenzyl)-2-((3-oxo-2-(thiophen-2-ylmethyl)isoindolin-1-yl)thio)acetamide (CAS 866008-25-5)
- 2-((4-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-phenylnicotinonitrile (CAS 330551-80-9)
- N-[(5-{[(4-tert-butylphenyl)methyl]sulfanyl}-4-ethyl-4H-1,2,4-triazol-3-yl)methyl]-4-chlorobenzamide (CAS 338962-52-0)
- Monascorubramin (CAS 3627-51-8)
- 2-[6-[2-(Trifluoromethyl)phenyl]pyridin-2-yl]acetonitrile (CAS 1261479-61-1)
- 5-Cyclopropyl-3(2H)-pyridazinone (CAS 1693577-72-8)
- (R)-4-(1-Aminoethyl)-N,N-dimethylaniline hydrochloride (CAS 1810074-57-7)
- Benzyl ((3S,4R)-4-methylpyrrolidin-3-yl)carbamate hydrochloride (CAS 1951441-29-4)
- 1-ethyl-3H-imidazo[4,5-c]pyridin-2-one (CAS 460739-65-5)
- 6-Bromo-2-hydroxyquinolin-4(1H)-one (CAS 2254506-51-7)
- Ethyl (2S)-2-({[4-(bromomethyl)phenyl]sulfonyl}amino)-4-methylpentanoate (CAS 141834-14-2)
- N-(4-Fluorobenzyl)-1-(1-(2-fluoroethyl)-1H-pyrazol-3-yl)methanamine hydrochloride (CAS 1856065-74-1)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
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