Methyl 5-((2-chlorophenyl)carbamoyl)-4-methyl-2-(3-methylbenzamido)thiophene-3-carboxylate CAS 335407-75-5
| CAS No. | 335407-75-5 |
| Molecular Formula | C22H19ClN2O4S |
| Molecular Weight | 442.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 442.92 g/mol gives Methyl 5-((2-chlorophenyl)carbamoyl)-4-methyl-2-(3-methylbenzamido)thiophene-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 5-((2-chlorophenyl)carbamoyl)-4-methyl-2-(3-methylbenzamido)thiophene-3-carboxylate (CAS 335407-75-5) is a high-purity analytical reference standard with the molecular formula C22H19ClN2O4S and a molecular weight of 442.92 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Methyl 5-((2-chlorophenyl)carbamoyl)-4-methyl-2-(3-methylbenzamido)thiophene-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 442.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H19ClN2O4S |
| Molecular Weight | 442.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- Methyl 2-(4-chlorobenzamido)-4-methyl-5-(p-tolylcarbamoyl)thiophene-3-carboxylate (CAS 351352-57-3)
- N-(2-Chloro-4,6-dimethylphenyl)-2-((5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 843616-40-0)
- Methyl 2-(3-chlorobenzamido)-4-methyl-5-(m-tolylcarbamoyl)thiophene-3-carboxylate (CAS 335406-72-9)
- Udenafil Impurity 3 (CAS CATO-C4X-33723)
- 2,7-Diiodonaphthalene (CAS 58556-77-7)
- N-(3-Aminophenyl)-4-fluorobenzenesulfonamide (CAS 436089-66-6)
- 2-(3-Butoxyphenyl)-6-chloroquinoline-4-carboxylic acid (CAS 932841-45-7)
- 1-Methyl-5-(trifluoromethyl)indoline-2,3-dione (CAS 23563-09-9)
- 3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2,4-thiadiazol-5-amine (CAS 1179362-69-6)
- 2-(1H-Benzoimidazol-2-yl)-N-(2-methoxy-ethyl)-acetamide (CAS 519152-81-9)
- (R)-1-(Benzo[d][1,3]dioxol-4-yl)ethan-1-amine (CAS 1213017-89-0)
- 2-(1-((3-Hydroxypropyl)amino)propyl)phenol (CAS 651304-81-3)
- 1-(3-ethyl-5-methyl-1-benzofuran-2-yl)ethanone (CAS 790263-82-0)
- (Des-Bromo)-Neuropeptide B (1-23) (human) (CAS 434897-64-0)
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