1-(4-Fluoro-3-(trifluoromethyl)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one CAS 1023441-47-5
| CAS No. | 1023441-47-5 |
| Molecular Formula | C18H17F4NO |
| Molecular Weight | 339.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-Fluoro-3-(trifluoromethyl)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1023441-47-5) is a high-purity analytical reference standard with the molecular formula C18H17F4NO and a molecular weight of 339.33 g/mol.
The molecular framework of 1-(4-Fluoro-3-(trifluoromethyl)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (C18H17F4NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 1-(4-Fluoro-3-(trifluoromethyl)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17F4NO |
| Molecular Weight | 339.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2-[3-(trifluoromethyl)phenyl]propanoic acid (CAS 68718-08-1)
- Ethyl 3-hydroxy-3-(2-oxoindolin-3-ylidene)propanoate (CAS 199190-70-0)
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- 2-Methylthio-6-phenyl-4H-thiopyran-4-one (CAS 113544-16-4)
- 2-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)piperidine (CAS 1041561-95-8)
- D-Trp25-Tirzepatide (CAS CATO-CPTD788909)
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