Glutathione Impurity N5 CAS 17297-99-3
| CAS No. | 17297-99-3 |
| Molecular Formula | C10H17N3O8S |
| Molecular Weight | 339.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Glutathione Impurity N5.
As a process- or degradation-related impurity, Glutathione Impurity N5 (CAS 17297-99-3, C10H17N3O8S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carbohydrate-derived structure, an amide group, a sulfone group, Glutathione Impurity N5 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 339.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17N3O8S |
| Molecular Weight | 339.32 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Glutathione Standards
- Glutathione-monoethyl ester (reduced) (CAS 92614-59-0)
- Glutathione-monoisopropyl ester (reduced) (CAS 97451-46-2)
- Glutathione Impurity 7 (CAS 3773-07-7)
- Glutathione-diethyl ester (reduced) (H-2238.0250) (CAS 97451-40-6)
- Glutathione-(glycine- (CAS 815610-65-2)
- Glutathione (CAS 1432061-73-6)
- Glutathione (1S, 2R)-Isomer (CAS 274260-05-8)
- Glutathione Reduced (CAS 70-18-8)
Recommended Standards
- Mesotrione (CAS 104206-82-8)
- 3-Methyl-2-((3-(trifluoromethyl)phenyl)sulfonamido)pentanoic acid (CAS 1008214-80-9)
- Cephacetrile Impurity 2 (CAS CATO-C4X-23112)
- 1-(4-Fluoro-3-(trifluoromethyl)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1023441-47-5)
- Bacitracin Impurity N (CAS CATO-C4X-155314)
- Brimonidine Impurity 34 (CAS CATO-C4X-156634)
- Darunavir Impurity 18 (CAS 1932330-83-0)
- Dodeca-2E,4E,8Z,10E-tetraenoic Acid Isobutylamide (CAS 75917-90-7)
- 1,3-Diphenylpropane-2-sulfonyl chloride (CAS 1275565-58-6)
- Z-Ser-Ala-OH (CAS 24787-87-9)
- Ketoprofen-d3 Methyl Ester (CAS 1189950-12-6)
- Ethyl 1-methyl-1H-indazole-4-carboxylate (CAS 1360438-58-9)
- 2-(2-Bromopyrimidin-5-yl)acetic acid (CAS 1379330-42-3)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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