2,3-Dichlorophenylacetic Acid CAS 10236-60-9
| CAS No. | 10236-60-9 |
| Molecular Formula | C8H6Cl2O2 |
| Molecular Weight | 205.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,3-Dichlorophenylacetic Acid.
2,3-Dichlorophenylacetic Acid (CAS 10236-60-9) is a high-purity analytical reference standard with the molecular formula C8H6Cl2O2 and a molecular weight of 205.04 g/mol.
The molecular framework of 2,3-Dichlorophenylacetic Acid (C8H6Cl2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2O2 |
| Molecular Weight | 205.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
Related Dichlorophenylacetic Standards
Recommended Standards
- 2-Chloro-2-(4-chlorophenyl)acetic acid (CAS 102333-77-7)
- 2-Amino-4,6-dichlorobenzamide (CAS 1044872-57-2)
- 3,6-Dichloro-N-methyl-2-pyridinecarboxamide (CAS 1021077-12-2)
- 3’,4’-Dichloro-2-hydroxyacetophenone (CAS 113337-38-5)
- 1-tert-butyl-3-ethylpyrazolo[3,4-d]pyrimidin-4-amine (CAS 1246816-12-5)
- 7-(Tert-butyl)-4-chloro-2-cyclopropyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine (CAS 917746-35-1)
- N-(4-Chloro-2-methoxy-5-methylphenyl)-2,4,6-trimethylbenzamide (CAS 449158-32-1)
- 5-Chloro-2-(2-isopropyl-5-methylphenoxy)aniline (CAS 946715-18-0)
- (R)-2-Amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid (CAS 1241680-33-0)
- Ethyl 2-(3,5-dimethyl-1-phenyl-1h-pyrazol-4-yl)-2-oxoacetate (CAS 956506-25-5)
- Methyl 3-iodo-4-(methylamino)benzoate (CAS 868540-77-6)
- 3-(3,5-Dimethyladamantan-1-yl)propanoic acid (CAS 2173996-24-0)
- tert-Butyl 3-methyl-4-(2-(methylthio)pyrimidin-4-yl)piperazine-1-carboxylate (CAS 1261235-87-3)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
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