5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione CAS 1023875-59-3
| CAS No. | 1023875-59-3 |
| Molecular Formula | C15H10ClF3N4S2 |
| Molecular Weight | 402.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione.
5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 1023875-59-3), molecular formula C15H10ClF3N4S2 and molecular weight 402.84 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 402.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10ClF3N4S2 |
| Molecular Weight | 402.84 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Chloro Standards
- N-(3-Chloro-4-(3-oxopiperazin-1-yl)phenyl)-2-(furan-2-yl)thiazole-4-carboxamide (CAS 1281040-83-2)
- 2-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)propanoyl)-N-phenylhydrazine-1-carbothioamide (CAS 339010-56-9)
- N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-2-methylpropyl)-4-methylbenzamide (CAS 477845-57-1)
- Methyl (3-((4-chloro-N-methylphenyl)sulfonamido)thiophene-2-carbonyl)glycinate (CAS 1251549-87-7)
- (5Z)-5-({2-[(2-chloro-1,3-thiazol-5-yl)methoxy]naphthalen-1-yl}methylidene)-1,3-thiazolidine-2,4-dione (CAS 860787-03-7)
- N-(3-Chloro-4-fluorophenyl)-2-({4-cyano-1,6-diazatricyclo[6.2.2.0^{2,7}]dodeca-2,4,6-trien-5-yl}sulfanyl)acetamide (CAS 728885-96-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3,4-dimethoxyphenethyl)acetamide (CAS 478079-17-3)
- 3-((2-Chloro-6-fluorobenzyl)oxy)-2-methyl-1-(4-nitrobenzyl)pyridin-4(1H)-one (CAS 303144-71-0)
Recommended Standards
- N-((3-(allylcarbamoyl)-4,5-dihydroisoxazol-5-yl)methyl)-3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamide (CAS 321432-38-6)
- 2-(6-(tert-Butyl)-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzyl acetate (CAS 1242157-24-9)
- Ethyl 5-(4-chlorophenyl)-5-hydroxy-1-(2-phenoxyacetyl)-4,5-dihydro-1H-pyrazole-3-carboxylate (CAS 6073-28-5)
- Copper, [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-κN1,κN1′]dichloro-, (SP-4-2)- (CAS 1264222-51-6)
- 2-Cyclopropanecarbonyl-1-benzofuran (CAS 1311316-29-6)
- 2-(((2h-Indazol-7-yl)amino)methyl)phenol (CAS 899366-68-8)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-benzyl-1H-imidazol-4-yl)propanoic acid (CAS 1417638-37-9)
- Doxapram Impurity 16 (CAS CATO-C4X-197316)
- 5-(4-Fluorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazole (CAS 515845-17-7)
- Isavuconazole Impurity 23 (CAS CATO-C4X-123623)
- N-(2-(dimethylamino)ethyl)-2-hydroxy-2,2-diphenylacetamide (CAS 31416-65-6)
- (E)-Pent-3-en-2-one (CAS 3102-33-8)
- (S)-1-(4-fluoro-3-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine (CAS 1270028-51-7)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
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