Ethyl 5-(4-chlorophenyl)-5-hydroxy-1-(2-phenoxyacetyl)-4,5-dihydro-1H-pyrazole-3-carboxylate CAS 6073-28-5
| CAS No. | 6073-28-5 |
| Molecular Formula | C20H19ClN2O5 |
| Molecular Weight | 402.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 5-(4-chlorophenyl)-5-hydroxy-1-(2-phenoxyacetyl)-4,5-dihydro-1H-pyrazole-3-carboxylate.
Ethyl 5-(4-chlorophenyl)-5-hydroxy-1-(2-phenoxyacetyl)-4,5-dihydro-1H-pyrazole-3-carboxylate (CAS 6073-28-5) is a high-purity analytical reference standard with the molecular formula C20H19ClN2O5 and a molecular weight of 402.83 g/mol.
The molecular framework of Ethyl 5-(4-chlorophenyl)-5-hydroxy-1-(2-phenoxyacetyl)-4,5-dihydro-1H-pyrazole-3-carboxylate (C20H19ClN2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H19ClN2O5 |
| Molecular Weight | 402.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
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Recommended Standards
- N-((3-(allylcarbamoyl)-4,5-dihydroisoxazol-5-yl)methyl)-3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamide (CAS 321432-38-6)
- (E)-({4-[4-(3-chlorobenzoyl)piperazin-1-yl]-3-nitrophenyl}methylidene)(methoxy)amine (CAS 383147-23-7)
- 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 1023875-59-3)
- (2E)-N-(4-Chlorophenyl)-3-(dimethylamino)-2-[(1E)-{[(4-nitrophenyl)methoxy]imino}methyl]prop-2-enamide (CAS 320417-86-5)
- Vitamin D2-d3 (CAS 1217448-46-8)
- (2,6-Difluorophenyl)(4-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone (CAS 1171447-96-3)
- Cyclohexyl 2-(4-fluorophenyl)ethyl ketone (CAS 898768-92-8)
- 2-Chloro-5-isopropoxy-3-nitropyridine (CAS 1935294-81-7)
- Atorvastatin Impurity N5 (CAS 1403667-07-1)
- 5-(3-Carboxypyridin-2-yl)isophthalic acid (CAS 1261937-68-1)
- (2E)-3-(2-Methoxyphenyl)-2-[(E)-1-methyl-1H-pyrrole-2-carbonyl]prop-2-enenitrile (CAS 900019-51-4)
- 2-(2,2,2-Trifluoroethoxy)pyridine-3-carboxylic acid (CAS 183368-79-8)
- Dienogest EP Impurity F (CAS 67473-36-3)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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