Rosuvastatin EP Impurity L Calcium(Mixture of Diastereomers) CAS 1024064-70-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1024064-70-7
Molecular Formula2*C22H29FN3O6S
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rosuvastatin EP Impurity L Calcium(Mixture of Diastereomers) CAS 1024064-70-7 chemical structure

Description

Structurally, Rosuvastatin EP Impurity L Calcium(Mixture of Diastereomers) (C22H29FN3O6SCa) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.5, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 522.62 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Rosuvastatin EP Impurity L Calcium(Mixture of Diastereomers) (CAS 1024064-70-7) is a certified pharmaceutical impurity reference standard with the molecular formula C22H29FN3O6SCa and a molecular weight of 522.62 g/mol.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular Formula2*C22H29FN3O6S Ca
Molecular Weight522.62 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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