Baricitinib Impurity 21 CAS 1024120-52-2
| CAS No. | 1024120-52-2 |
| Molecular Formula | C7H11BrN2O |
| Molecular Weight | 219.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Baricitinib Impurity 21 (CAS 1024120-52-2, C7H11BrN2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a hydroxyl group, an ether linkage, bromine substitution, Baricitinib Impurity 21 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Baricitinib Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H11BrN2O |
| Molecular Weight | 219.08 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Baricitinib Standards
- Baricitinib Impurity 29 (CAS 2140326-23-2)
- Baricitinib Impurity 9 (CAS CATO-C4X-22609)
- Baricitinib Impurity 82 (CAS CATO-C4X-226082)
- Baricitinib Impurity 69 (CAS CATO-C4X-226069)
- Baricitinib Impurity 70 (CAS CATO-C4X-226070)
- Baricitinib Impurity 94 (CAS CATO-C4X-226094)
- Baricitinib Impurity 85 (CAS CATO-C4X-226085)
- Baricitinib Impurity 68 (CAS CATO-C4X-226068)
Recommended Standards
- Ruxolitinib Impurity 62 (CAS CATO-C4X-205862)
- 2-Methylpyridine-3-boronic Acid Pinacol Ester (CAS 1012084-56-8)
- 5-BROMO-1(3H)-ISOBENZOFURANONE 5-BROMO-1,3-DIHYDRO-2-BENZOFURAN-1-ONE 5-BROMO-3-HYDROISOBENZOFURAN-1-ONE 5-BROMO-3H-ISOBENZOFURAN-1-ONE 5-BROMOISOBENZOFURAN-1(3H)-ONE 64169-34-2 BC004588 (CAS 64169-34-2)
- 3-Methylpyridine-4-boronic Acid Pinacol Ester (CAS 1032358-00-1)
- Tofacitinib Impurity 197 (CAS CATO-C4X-1079197)
- Tucatinib Impurity N6 (CAS 2307628-67-5)
- Levocabastine EP impurity E (CAS 105452-51-5)
- 8-Methoxy-2-(phenylamino)-4H-chromene-3-carboxamide (CAS 1260951-20-9)
- IR-825 (CAS 1558079-49-4)
- 3-(3-Thienyl)phenylboronic acid (CAS 475206-83-8)
- 2-Methoxy-6-methyl-4-(trifluoromethyl)pyridine (CAS 1379091-35-6)
- 2-(1-Methyl-3-oxopiperazin-2-yl)acetic acid hydrochloride (CAS 1219270-94-6)
- 4-((1,3-Dioxolan-2-yl)methyl)pyridine (CAS 760211-59-4)
- Anti-Inflammatory Peptide 3 (CAS 118850-73-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com