Baricitinib Impurity 9 CAS CATO-C4X-22609
| CAS No. | CATO-C4X-22609 |
| Molecular Formula | C10H9N5O |
| Molecular Weight | 215.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Baricitinib Impurity 9 (CAS CATO-C4X-22609, C10H9N5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H9N5O, Baricitinib Impurity 9 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 215.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9N5O |
| Molecular Weight | 215.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Baricitinib Standards
- Baricitinib Impurity 82 (CAS CATO-C4X-226082)
- Baricitinib Impurity 21 (CAS 1024120-52-2)
- Baricitinib Impurity 29 (CAS 2140326-23-2)
- Baricitinib Impurity 94 (CAS CATO-C4X-226094)
- Baricitinib Impurity 85 (CAS CATO-C4X-226085)
- Baricitinib Impurity 68 (CAS CATO-C4X-226068)
- Baricitinib Impurity 86 (CAS CATO-C4X-226086)
- Baricitinib Impurity 69 (CAS CATO-C4X-226069)
Recommended Standards
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- Granisetron EP Impurity E (CAS 76272-56-5)
- Verteporfin Impurity 4 (CAS CATO-C4X-35494)
- 1-(4-Bromobutyl)-1,2,3-triazole (CAS 1793087-89-4)
- 4-Bromo-2-methoxybenzonitrile (CAS 330793-38-9)
- 1,4-Dihydroxy-2-morpholinoanthracene-9,10-dione (CAS 4644-03-5)
- Evocalcet impurity 54 (CAS CATO-C4X-248554)
- Ethyl (2Z)-2-chloro-2-[2-(2-methylphenyl)hydrazin-1-ylidene]acetate (CAS 64989-46-4)
- N1-ethyl-N1-(1-methylpiperidin-4-yl)ethane-1,2-diamine (CAS 1353948-29-4)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
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