2-(Benzo[d][1,3]dioxol-5-yl)-N-isopentyl-1-oxo-3-(pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide CAS 1024448-61-0
| CAS No. | 1024448-61-0 |
| Molecular Formula | C27H27N3O4 |
| Molecular Weight | 457.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(Benzo[d][1,3]dioxol-5-yl)-N-isopentyl-1-oxo-3-(pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide (CAS 1024448-61-0), molecular formula C27H27N3O4 and molecular weight 457.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Benzo[d][1,3]dioxol-5-yl)-N-isopentyl-1-oxo-3-(pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide (C27H27N3O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H27N3O4 |
| Molecular Weight | 457.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
Related Benzo Standards
- 2-(Benzo[d]thiazol-2(3H)-ylidene)-2-(2-((4-(morpholinomethyl)benzyl)oxy)pyrimidin-4-yl)acetonitrile (CAS 541507-14-6)
- 4-(Benzo[d]thiazol-2-ylthio)-3-nitrobenzyl 2-chlorobenzoate (CAS 320424-23-5)
- 4-(Benzo[d][1,3]dioxol-5-yl)-3-(2,4-dichlorophenoxy)-1-(4-methoxyphenyl)azetidin-2-one (CAS 946386-94-3)
- (E)-4-(benzo[d][1,3]dioxol-5-yl)-2-(4-methoxystyryl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile (CAS 866142-84-9)
- 4-(Benzo[d][1,3]dioxol-5-yl)-2-((3-methoxybenzyl)thio)-1,4-dihydro-5H-indeno[1,2-d]pyrimidin-5-one (CAS 861211-19-0)
- 4-(3-(Benzo[d][1,3]dioxol-5-yl)-1H-pyrazol-5-yl)-1-((2-nitrophenyl)sulfonyl)piperidine (CAS 1030386-38-9)
- (1-(Benzo[c][1,2,5]thiadiazol-4-ylsulfonyl)piperidine-4-carbonyl)-L-methionine (CAS 957029-97-9)
- 2-(Benzo[d][1,3]dioxol-5-ylamino)-2-oxoethyl 2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 380190-92-1)
Recommended Standards
- Ruxolitinib Impurity 92 (CAS CATO-C4X-205892)
- H-Tyr-Tyr-Leu-OH (CAS 117961-24-7)
- Cefmetazole Impurity 35 (CAS CATO-C4X-150735)
- Deflazacort 6β-Hydroxy (CAS 1262053-48-4)
- 7-Oxo-7H-[1,3]thiazolo[3,2-a]pyrimidine-5-carboxylic acid hydrate (CAS 1609395-62-1)
- [5-Chloro-2-(propan-2-yloxy)pyridin-4-yl]methanol (CAS 1602043-24-2)
- N-(2,3-dimethylcyclohexyl)-2-fluoropyridine-4-carboxamide (CAS 1291646-99-5)
- 4-(4-(Methylsulfonyl)phenyl)-2-(3-(trifluoromethyl)phenyl)thiazole (CAS 861208-08-4)
- (2E)-3-[2-(2,4-Dichlorophenoxy)phenyl]-2-{4-[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]-1,3-thiazol-2-yl}prop-2-enenitrile (CAS 866019-87-6)
- 1-(2-Methoxypyridin-3-yl)thiourea (CAS 1103427-47-9)
- 2-(3-Bromo-6-cyano-2-nitrophenyl)acetic acid (CAS 1807045-30-2)
- Ethyl 2-amino-4-methylfuran-3-carboxylate (CAS 1505673-54-0)
- Benzyl (3-aminocyclobutyl)carbamate (CAS 1188264-84-7)
- T-Peptide (CAS 2022956-62-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com