Ruxolitinib Impurity 92 CAS CATO-C4X-205892
| CAS No. | CATO-C4X-205892 |
| Molecular Formula | C20H23N7O4S |
| Molecular Weight | 457.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ruxolitinib Impurity 92.
CATO supplies Ruxolitinib Impurity 92 (CAS CATO-C4X-205892), a pharmacopoeial impurity reference standard (molecular formula C20H23N7O4S, MW 457.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Ruxolitinib Impurity 92 (C20H23N7O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 457.51 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ruxolitinib Impurity 92 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23N7O4S |
| Molecular Weight | 457.51 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 93 (CAS CATO-C4X-205893)
- Ruxolitinib Impurity 215 (CAS CATO-C4X-2058215)
- Ruxolitinib Impurity 91 (CAS CATO-C4X-205891)
- Ruxolitinib Impurity 54 (CAS CATO-C4X-205854)
- Ruxolitinib Impurity 8 Trifluoroacetate (CAS 2606144-44-7(free base))
- Ruxolitinib Impurity 55 (CAS CATO-C4X-205855)
- Ruxolitinib Impurity 173 (CAS 1236032-96-4)
- Ruxolitinib Impurity 56 (CAS CATO-C4X-205856)
Recommended Standards
- Cefmetazole Impurity 35 (CAS CATO-C4X-150735)
- 2-(Benzo[d][1,3]dioxol-5-yl)-N-isopentyl-1-oxo-3-(pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide (CAS 1024448-61-0)
- Cefmetazole Impurity 19 (CAS CATO-C4X-150719)
- H-Tyr-Tyr-Leu-OH (CAS 117961-24-7)
- Luliconazole impurity 23 (CAS CATO-C4X-285323)
- Trazodone impurity 49 (CAS CATO-C4X-177249)
- Inosine impurity 5 (CAS 255716-10-0)
- 5-Methyl-4-(trifluoromethyl)picolinic acid (CAS 1211535-48-6)
- Tert-butyl 9-benzyl-1,9-diazaspiro[5.5]Undecane-1-carboxylate (CAS 1373350-42-5)
- 4-(1-Methyl-1h-1,2,4-triazol-5-yl)-2-nitroaniline (CAS 1249332-57-7)
- 3-Bromo-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole (CAS 1781305-41-6)
- 2-(Thiazol-5-yl)ethanamine dihydrochloride (CAS 7730-82-7)
- 4,5,6,7-Tetrahydro-furo[3,2-c]pyridine-4-methanol (CAS 129823-17-2)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com