N-[4-(Trifluoromethoxy)phenyl]-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide CAS 1024492-48-5
| CAS No. | 1024492-48-5 |
| Molecular Formula | C18H16F6N4OS |
| Molecular Weight | 450.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-[4-(Trifluoromethoxy)phenyl]-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide (CAS 1024492-48-5) is a high-purity analytical reference standard with the molecular formula C18H16F6N4OS and a molecular weight of 450.40 g/mol.
Based on its molecular formula C18H16F6N4OS, N-[4-(Trifluoromethoxy)phenyl]-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 450.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[4-(Trifluoromethoxy)phenyl]-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16F6N4OS |
| Molecular Weight | 450.40 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
- 4,6-Bis(3-(trifluoromethoxy)phenoxy)pyrimidin-5-amine (CAS 864371-12-0)
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- 4,5-Bis(3-(trifluoromethoxy)phenyl)-2-(trifluoromethyl)pyridine (CAS 1261756-09-5)
- 4-Phenyl-3-{1-[2-(trifluoromethoxy)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775458-57-5)
- 4-Phenyl-3-{1-[3-(trifluoromethoxy)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775467-92-9)
- 4-Phenyl-3-{1-[4-(trifluoromethoxy)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775532-51-8)
Recommended Standards
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- 2-(4-Nitrophenyl)-2H-naphtho[1,2-d][1,2,3]triazole-6,8-disulfonic acid (CAS 130-34-7)
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- 4-[5-Amino-4-(ethoxycarbonyl)-1h-pyrazol-1-yl]benzoic acid (CAS 926203-48-7)
- N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3,4,5-triiodobenzamide (CAS 1024504-66-2)
- 2-(1-Ethyl-1h-1,2,4-triazol-5-yl)ethan-1-amine (CAS 1250490-69-7)
- 2-methoxypentanenitrile (CAS 98548-71-1)
- Probenecid (CAS 57-66-9)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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