Probenecid CAS 57-66-9
| CAS No. | 57-66-9 |
| Molecular Formula | C13H19NO4S |
| Molecular Weight | 285.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Probenecid (C13H19NO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Probenecid (CAS 57-66-9), a certified reference material (molecular formula C13H19NO4S, MW 285.36 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H19NO4S |
| Molecular Weight | 285.36 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Probenecid Standards
- Probenecid Impurity 9 (CAS 141284-78-8)
- Probenecid Impurity 10 (CAS 141284-79-9)
- Probenecid EP Impurity D (CAS 70190-76-0)
- Probenecid EP Impurity B (CAS 723-42-2)
- Probenecid Isopropyl Ester (CAS 70190-78-2)
- Probenecid Impurity 4 (CAS 1206-37-7)
- Probenecid EP Impurity C (CAS CATO-C4X-29518)
- Probenecid EP Impurity A (CAS 636-78-2)
Recommended Standards
- Venetoclax Impurity 44 (CAS CATO-C4X-249544)
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- PROTHOATE (CAS 2275-18-5)
- 6-Bromo-3-methyl-1H-indole-4-carboxylic acid (CAS 1360956-94-0)
- N-(2,6-Diphenylpyrimidin-4-yl)acetamide (CAS 820961-40-8)
- Sodium 5-bromopyridine-2-sulfinate (CAS 2137712-61-7)
- 8-Methyl-3,8-diaza-bicyclo[3.2.1]octane (CAS 51102-42-2)
- 3-Bromo-2-(3-bromo-2-methylpropyl)thiophene (CAS 1496893-62-9)
- Cefoperazone Impurity 18 (CAS CATO-C4X-114918)
- 3-Methyl-5-(3-methylbutyl)-1,3-thiazolidine-2,4-dione (CAS 861206-58-8)
- 4-([1,1'-Biphenyl]-4-yl)cyclohexanone (CAS 78531-65-4)
- Ethyl 2-(chloromethyl)-6-methyl-4-oxo-3h,4h-furo[2,3-d]pyrimidine-5-carboxylate (CAS 851722-05-9)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com