3-(2-Bromobenzo[b]thiophen-3-yl)propanoic acid CAS 10245-72-4
| CAS No. | 10245-72-4 |
| Molecular Formula | C11H9BrO2S |
| Molecular Weight | 285.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(2-Bromobenzo[b]thiophen-3-yl)propanoic acid.
CATO supplies 3-(2-Bromobenzo[b]thiophen-3-yl)propanoic acid (CAS 10245-72-4), a certified reference material (molecular formula C11H9BrO2S, MW 285.16 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2-Bromobenzo[b]thiophen-3-yl)propanoic acid (C11H9BrO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9BrO2S |
| Molecular Weight | 285.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 1 |
Related Bromobenzo Standards
- Ethyl 7-bromobenzo[b]thiophene-2-carboxylate (CAS 1355171-39-9)
- Ethyl 5-bromobenzo[b]thiophene-3-carboxylate (CAS 1824075-12-8)
- Ethyl 4-bromobenzo[b]thiophene-3-carboxylate (CAS 1824415-17-9)
- Ethyl 3-bromobenzo[b]thiophene-6-carboxylate (CAS 2090569-45-0)
- Ethyl 7-bromobenzo[b]thiophene-3-carboxylate (CAS 2090834-61-8)
- Ethyl 6-bromobenzo[d]thiazole-2-carboxylate (CAS 1188024-51-2)
- Ethyl 7-bromobenzo[d]thiazole-2-carboxylate (CAS 1188170-07-1)
- Ethyl 2-bromobenzo[d]thiazole-5-carboxylate (CAS 1446410-03-2)
Recommended Standards
- 5-Bromo-2-[(4-methyl-4h-1,2,4-triazol-3-yl)sulfanyl]aniline (CAS 1019441-45-2)
- Ethyl 6-bromo-1-benzothiophene-2-carboxylate (CAS 105191-64-8)
- 8-Methoxyquinoline-5-boronic acid pinacol ester, 97% (CAS 916162-54-4)
- 1142208-31-8 4-Amino-6-(3-bromophenyl)-1,6-dihydro-1,3,5-triazine-2-thiol (CAS 1142208-31-8)
- 2-(6-Chloropyridin-2-yl)hydrazine-1-carboxamide (CAS 320415-91-6)
- Tert-butyl (3S,8aS)-3-carbamoylhexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (CAS 1266230-31-2)
- Tert-butyl 2-(imino(3-(trifluoromethyl)phenyl)methyl)hydrazine-1-carboxylate (CAS 1053655-65-4)
- N-Acetyl-L-serine (CAS 16354-58-8)
- 2-(Trifluoromethoxy)benzenesulfonyl Chloride (CAS 103008-51-1)
- 2,4-Dichloro-8-(4-fluorophenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine (CAS 1263868-84-3)
- 3-(4-Aminophenyl)pyridin-4-amine (CAS 1258629-77-4)
- Cloransulam-Methyl Impurity 10 (CAS CATO-C4X-317010)
- 2-Vinylpropane-1,3-diol (CAS 922167-76-8)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com