Methyl 2-hydroxy-6-(trifluoromethyl)benzoate CAS 1024605-95-5
| CAS No. | 1024605-95-5 |
| Molecular Formula | C9H7F3O3 |
| Molecular Weight | 220.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 2-hydroxy-6-(trifluoromethyl)benzoate (CAS 1024605-95-5) is a high-purity analytical reference standard with the molecular formula C9H7F3O3 and a molecular weight of 220.15 g/mol.
Methyl 2-hydroxy-6-(trifluoromethyl)benzoate (C9H7F3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Methyl 2-hydroxy-6-(trifluoromethyl)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7F3O3 |
| Molecular Weight | 220.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Methyl Standards
- Methyl 2-hydroxy-2-(2,4,5-trifluorophenyl)acetate (CAS 1036273-10-5)
- 2-(4-Hydroxy-3-(trifluoromethyl)phenyl)acetic acid (CAS 1042703-41-2)
- 2-Hydroxy-4’-(trifluoromethoxy)acetophenone (CAS 1148005-60-0)
- Methyl 4-hydroxy-3-(trifluoromethyl)benzoate (CAS 115933-50-1)
- 2-Hydroxy-4-methyl-6-(trifluoromethyl)nicotinamide (CAS 116548-07-3)
- (2s)-2-Hydroxy-2-[3-(trifluoromethyl)phenyl]acetic acid (CAS 1198319-99-1)
- Methyl 2-hydroxy-5-(trifluoromethyl)benzoate (CAS 1261478-26-5)
- 2-[4-hydroxy-2-(trifluoromethyl)phenyl]acetic acid (CAS 1261569-12-3)
Recommended Standards
- 6-((2,2,2-Trifluoroethyl)amino)nicotinic acid (CAS 1019388-10-3)
- 2,2-Difluoro-2-(3-fluoro-4-methoxyphenyl)acetic acid (CAS 1027513-93-4)
- 2,2-Dihydroxy-1-[4-(trifluoromethyl)phenyl]ethanone (CAS 101906-05-2)
- Methyl 2-amino-6-(trifluoromethyl)nicotinate (CAS 1034131-63-9)
- 2-Bromo-8-(3,5-difluorophenoxy)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridine (CAS 2443488-22-8)
- 6-tert-Butyl-4-hydroxy-pyran-2-one (CAS 857248-84-1)
- Tert-butyl (R)-(3-formylcyclopent-2-en-1-yl)carbamate (CAS 1868051-15-3)
- (5-Nitro-1H-benzimidazol-2-yl)methanol (CAS 20034-00-8)
- (3R,4S)-4-methylpiperidin-3-amine (CAS 691351-71-0)
- 5-(1-Methyl-1h-pyrazol-4-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1339374-11-6)
- Mirogabalin Impurity 87 (CAS CATO-C4X-292487)
- N,N-diethyl-2-methylbenzamide (CAS 2728-04-3)
- (R)-Thiazolidine-4-carbonitrile (CAS 463348-53-0)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
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