(2Z)-2-{[4-(difluoromethoxy)phenyl]methylidene}-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one CAS 1025637-49-3
| CAS No. | 1025637-49-3 |
| Molecular Formula | C19H16F2O4 |
| Molecular Weight | 346.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2Z)-2-{[4-(difluoromethoxy)phenyl]methylidene}-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one (CAS 1025637-49-3) is a high-purity analytical reference standard with the molecular formula C19H16F2O4 and a molecular weight of 346.32 g/mol.
(2Z)-2-{[4-(difluoromethoxy)phenyl]methylidene}-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one (C19H16F2O4) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (2Z)-2-{[4-(difluoromethoxy)phenyl]methylidene}-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16F2O4 |
| Molecular Weight | 346.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Z Standards
- 2-((3-(2-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)methoxy)benzaldehyde (CAS 1707576-19-9)
- 4-((3-(2-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)methoxy)benzaldehyde (CAS 1707576-21-3)
- 3-((3-(2-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)methoxy)benzaldehyde (CAS 1710660-93-7)
- 1-(4-(Difluoromethoxy)phenyl)-2-(ethylthio)-5-phenyl-1H-imidazole (CAS 1226449-16-6)
- Methyl 2-(difluoromethoxy)-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 2787517-20-6)
- Methyl 6-(4-(difluoromethoxy)phenyl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011397-96-8)
- 2-(Difluoromethoxy)-N-(4-(2-methyloxazol-5-yl)phenyl)benzamide (CAS 1311855-96-5)
- 2-(4-(Difluoromethoxy)-3-((methoxymethoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1623766-69-7)
Recommended Standards
- Lemborexant Impurity 43 (CAS CATO-C4X-304243)
- Ethyl 2-(2-((4-(trifluoromethoxy)phenyl)amino)thiazol-5-yl)acetate (CAS 1092959-60-8)
- Pazufloxacin Impurity 2 (CAS CATO-C4X-23322)
- N,N-dimethyl-4-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 1227954-33-7)
- 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-2-methylpyridine (CAS 1408003-73-5)
- 2-((2,5-Difluorophenyl)carbamoyl)cyclopropane-1-carboxylic acid (CAS 866150-60-9)
- 5-(Bromomethyl)-3-(difluoromethyl)-6-iodopyridin-2-amine (CAS 1805213-10-8)
- 3-Fluoroquinolin-5-ol (CAS 1261729-67-2)
- Methyl 5-bromoindoline-7-carboxylate (CAS 860624-88-0)
- 1-(3-Bromophenyl)-4-chlorobutan-1-one (CAS 494863-34-2)
- Dodec-11-yn-1-amine (CAS 1379331-41-5)
- 3-Bromo-2-(trifluoromethyl)pyridine-4-acetic acid (CAS 1227595-64-3)
- 4-Fluoro-2-methylbenzaldehyde (CAS 63082-45-1)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com