Methyl 6-(thiophen-2-yl)-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate CAS 1027511-29-0
| CAS No. | 1027511-29-0 |
| Molecular Formula | C14H9F3N2O2S |
| Molecular Weight | 326.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Methyl 6-(thiophen-2-yl)-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (CAS 1027511-29-0) is a high-purity analytical reference standard with the molecular formula C14H9F3N2O2S and a molecular weight of 326.29 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Methyl 6-(thiophen-2-yl)-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 326.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H9F3N2O2S |
| Molecular Weight | 326.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Methyl 5-(thiophen-2-yl)-7-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxylate (CAS 1027511-26-7)
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- N-((1-(Thiophen-2-yl)cyclopropyl)methyl)-2-(trifluoromethyl)benzamide (CAS 1207029-10-4)
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- Methyl 5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 313249-33-1)
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Recommended Standards
- Phenanthren-9-yl trifluoromethanesulfonate (CAS 120270-47-5)
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- Tris(4-hydroxyphenyl)phosphineoxide (CAS 797-71-7)
- (2E)-3-[(4-Chlorophenyl)amino]-1-{4-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-en-1-one (CAS 477889-40-0)
- 2-(2-(Azepan-1-yl)-4-(3-chloro-4-methoxyphenyl)thiazol-5-yl)acetic acid (CAS 1443289-99-3)
- 5-Chloropyridazine-3-carboxylic acid (CAS 1211587-01-7)
- Benzyl 1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate (CAS 147610-97-7)
- N-(3-Amino-2-methylphenyl)-2-methylbenzamide (CAS 926211-32-7)
- Methyl (R)-3-(2,5-dioxooxazolidin-4-yl)propanoate (CAS 1676-88-6)
- Diethyl (2S,4S)-1-benzylazetidine-2,4-dicarboxylate (CAS 174309-29-6)
- 4-Bromo-1-(butan-2-yl)-1h-pyrazole (CAS 1179304-86-9)
- 3-(2-(4-Bromophenoxy)ethyl)-5-methylbenzo[d]oxazol-2(3H)-one (CAS 638142-11-7)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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