2-(2-(Azepan-1-yl)-4-(3-chloro-4-methoxyphenyl)thiazol-5-yl)acetic acid CAS 1443289-99-3
| CAS No. | 1443289-99-3 |
| Molecular Formula | C18H21ClN2O3S |
| Molecular Weight | 380.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(2-(Azepan-1-yl)-4-(3-chloro-4-methoxyphenyl)thiazol-5-yl)acetic acid (CAS 1443289-99-3), a certified reference material (molecular formula C18H21ClN2O3S, MW 380.89 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2-(Azepan-1-yl)-4-(3-chloro-4-methoxyphenyl)thiazol-5-yl)acetic acid (C18H21ClN2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H21ClN2O3S |
| Molecular Weight | 380.89 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Azepan Standards
- 3-(6-(Azepan-1-yl)pyridin-3-yl)-5-((4-methoxyphenoxy)methyl)-1,2,4-oxadiazole (CAS 1358349-74-2)
- 1-(Azepan-1-yl)-2-((4-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyridazin-7-yl)thio)ethan-1-one (CAS 1105201-10-2)
- 2-(3-(Azepan-1-ylsulfonyl)-2-oxopyridin-1(2H)-yl)-N-cyclopentylacetamide (CAS 1251609-56-9)
- 1-(Azepan-1-yl)-2-((3-(p-tolyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)ethan-1-one (CAS 852375-32-7)
- 3-(Azepan-1-ylsulfonyl)-N-(5-methylthiazol-2-yl)benzamide (CAS 865267-78-3)
- 1-(Azepan-1-yl)-2-((3-(p-tolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)ethan-1-one (CAS 863459-07-8)
- 2-((2-(Azepan-1-yl)-6-methylpyrimidin-4-yl)oxy)-N-(2-ethyl-6-methylphenyl)acetamide (CAS 1226449-30-4)
- 2-((2-(Azepan-1-yl)-6-methylpyrimidin-4-yl)oxy)-N-ethyl-N-(m-tolyl)acetamide (CAS 1226450-18-5)
Recommended Standards
- 3-(4-(tert-Butyldimethylsilyl)-5-chloro-3,6-difluoropyridin-2-yl)-1H-pyrazolo[3,4-b]pyridine (CAS 1321925-14-7)
- 2-((4-Chlorophenyl)thio)-N'-(diphenylmethylene)acetohydrazide (CAS 341968-00-1)
- N-(3-Chloro-4-fluorophenyl)-3-(2-methyl-4-(thiophen-2-yl)thiazol-5-yl)propanamide (CAS 1017663-07-8)
- 2-(4-Chlorophenoxy)-N-(2-morpholino-2-(thiophen-2-yl)ethyl)acetamide (CAS 898601-48-4)
- 2,4-Bis(benzyloxy)benzaldehyde (CAS 13246-46-3)
- (1S,5R)-6-Oxabicyclo[3.2.0]heptane-3,7-dione (CAS 1638744-42-9)
- 2-((Tetrahydrofuran-3-yl)oxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1315351-11-1)
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- 4-(3-Fluorophenyl)pyrrolidine-3-carboxylic acid (CAS 1047654-47-6)
- 4-(Difluoromethyl)-5-fluoro-2-nitrophenol (CAS 2092102-06-0)
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- ((1S,4s)-cyclohexane-1,4-diyl)dimethanamine (CAS 10029-09-1)
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