Doxazosin Impurity 12 CAS 102932-26-3
| CAS No. | 102932-26-3 |
| Molecular Formula | C22H23N5O5 |
| Molecular Weight | 437.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Doxazosin Impurity 12 (CAS 102932-26-3, C22H23N5O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Doxazosin Impurity 12 (C22H23N5O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Doxazosin Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H23N5O5 |
| Molecular Weight | 437.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 5 |
Related Doxazosin Standards
- Doxazosin Impurity 11 (CAS 102932-25-2)
- S-Doxazosin (CAS 104874-86-4)
- R-Doxazosin (CAS 70918-17-1)
- Doxazosin impurity 21 (CAS CATO-C4X-162321)
- Doxazosin EP Impurity C (CAS 617677-53-9)
- Doxazosin Impurity 13 (CAS 102932-28-5)
- Doxazosin Impurity 14 (CAS 102932-29-6)
- Doxazosin Impurity 22 (CAS CATO-C4X-162322)
Recommended Standards
- Fluticasone Impurity 79 (CAS CATO-C4X-165079)
- Cefdinir CP Impurity S (CAS 127770-93-8)
- Topotecan Impurity 4 (CAS 1398723-05-1)
- Cefdinir Impurity 30 (CAS CATO-C4X-121030)
- (R,S)-Formoterol Impurity (CAS 67346-51-4)
- Ganirelix lmpurity 7 (CAS CATO-C4X-23737)
- Alverine Impurity 7 HCl (CAS 1199-99-1(free base))
- 2-(3,5-Dimethylbenzoyl)phenyl acetate (CAS 890099-15-7)
- (2E)-N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-cyano-3-(4-methylphenyl)prop-2-enamide (CAS 1327169-49-2)
- Methyl 4-Morpholinobenzoate (CAS 23676-05-3)
- 1-((3-Methoxypropyl)sulfonyl)piperazine (CAS 1339106-33-0)
- N-(4-bromo-2-methoxyphenyl)-2,2,2-trifluoroacetamide (CAS 870838-52-1)
- 1-DEOXY-1-NITRO-D-GALACTITOL (CAS 20971-06-6)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com