Doxazosin Impurity 14 CAS 102932-29-6
| CAS No. | 102932-29-6 |
| Molecular Formula | C23H25N5O6 |
| Molecular Weight | 467.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C23H25N5O6, Doxazosin Impurity 14 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 467.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Doxazosin Impurity 14 (CAS 102932-29-6, C23H25N5O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H25N5O6 |
| Molecular Weight | 467.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 5 |
Related Doxazosin Standards
- Doxazosin Impurity 13 (CAS 102932-28-5)
- Doxazosin impurity 21 (CAS CATO-C4X-162321)
- Doxazosin Impurity 22 (CAS CATO-C4X-162322)
- S-Doxazosin (CAS 104874-86-4)
- R-Doxazosin (CAS 70918-17-1)
- Doxazosin Impurity 11 (CAS 102932-25-2)
- Doxazosin Impurity 12 (CAS 102932-26-3)
- Doxazosin EP Impurity C (CAS 617677-53-9)
Recommended Standards
- K-252A (CAS 99533-80-9)
- Dexlansoprazole Impurity 7 (CAS 1781244-56-1)
- (2R,3R,4S,5R)-2-(6-(Ethylamino)-2-(4-(4-methoxyphenyl)-1H-pyrazol-1-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 765299-59-0)
- Flurbiprofen Impurity 98 (CAS CATO-C4X-144498)
- Fosaprepitant impurity 56（S,S,S） (CAS CATO-C4X-116856)
- Baloxavir Impurity 135 (CAS CATO-C4X-2108135)
- Cilnidipine Impurity 18 (CAS 52326-05-3)
- Posaconazole Impurity 35 (CAS 1370190-85-4)
- N-[2-(4-Isopropylphenoxy)propyl]-N-(3-methoxypropyl)amine (CAS 1040680-87-2)
- 3-Amino-2-(3-methoxyphenyl)quinazolin-4(3H)-one (CAS 388109-22-6)
- 2-Chloro-5-fluoro-4-nitrobenzonitrile (CAS 1273585-09-3)
- Vinyl Propionate (stabilized with MEHQ) (CAS 105-38-4)
- 4-amino-3-tert-butylphenol (CAS 24197-41-9)
- Insulin Lispro (CAS 133107-64-9)
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