(2R,3R,4S,5R)-2-(7-Amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol CAS 10299-44-2
| CAS No. | 10299-44-2 |
| Molecular Formula | C9H12N6O4 |
| Molecular Weight | 268.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2R,3R,4S,5R)-2-(7-Amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 10299-44-2), molecular formula C9H12N6O4 and molecular weight 268.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2R,3R,4S,5R)-2-(7-Amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (C9H12N6O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12N6O4 |
| Molecular Weight | 268.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 6 |
Recommended Standards
- tert-Butyl 3-(trifluoroacetamido)azetidine-1-carboxylate (CAS 1002355-90-9)
- 2,3,3'-Trifluoro-4,4'-dimethoxy-1,1'-biphenyl (CAS 1046758-86-4)
- 1,2-Phenylene-bis-maleimide (CAS 13118-04-2)
- 2-Naphthalenecarboxylic acid, 8-(trifluoromethyl)-, ethyl ester (CAS 1092352-45-8)
- Ethyl 1-(trifluoromethyl)cyclohexane-1-carboxylate (CAS 403981-04-4)
- 1,4-Di-tert-butyl 2-methyl 1,4-diazepane-1,2,4-tricarboxylate (CAS 1381946-82-2)
- 1-tert-butyl-6-chloro-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1464973-29-2)
- 5-Bromo-2-(methylsulfonyl)-4-pyrimidinecarboxylic Acid (CAS 30321-94-9)
- Ornidazole Impurity 102 (CAS CATO-C4X-1331102)
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(phenylcarbamoyl)amino]-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338399-32-9)
- N-cyclopropyl-N-(1-(4-fluorophenyl)ethyl)glycine (CAS 1353952-19-8)
- 2,2-Dimethyl-3-(methylamino)propan-1-ol (CAS 16047-86-2)
- N-2-Naphthalenyl-L-leucine (CAS 99631-79-5)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
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