5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(phenylcarbamoyl)amino]-4,5-dihydro-1,2-oxazole-3-carboxamide CAS 338399-32-9
| CAS No. | 338399-32-9 |
| Molecular Formula | C18H16ClF3N6O3 |
| Molecular Weight | 456.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(phenylcarbamoyl)amino]-4,5-dihydro-1,2-oxazole-3-carboxamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(phenylcarbamoyl)amino]-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338399-32-9), a certified reference material (molecular formula C18H16ClF3N6O3, MW 456.81 g/mol) for analytical method development and quality control.
Based on its molecular formula C18H16ClF3N6O3, 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(phenylcarbamoyl)amino]-4,5-dihydro-1,2-oxazole-3-carboxamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 456.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(phenylcarbamoyl)amino]-4,5-dihydro-1,2-oxazole-3-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16ClF3N6O3 |
| Molecular Weight | 456.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
Related chloro Standards
- 3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[(1E)-({[3-(trifluoromethyl)phenyl]methoxy}amino)methylidene]thiourea (CAS 477873-19-1)
- {5-chloro-1-methyl-3-[(phenylsulfanyl)methyl]-1H-pyrazol-4-yl}methyl N-(3,4-dichlorophenyl)carbamate (CAS 400087-20-9)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3-methoxybenzyl)-1-methyl-1H-imidazole-5-carboxamide (CAS 339278-17-0)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(4-fluorophenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-05-1)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)-N-(3,5-dimethylphenyl)benzenesulfonamide (CAS 338775-29-4)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(2,3-dimethylphenyl)benzene-1-sulfonamide (CAS 338775-36-3)
- 2-Chloro-N'-(2-(4-methoxyphenyl)imidazo[1,2-a]pyridine-6-carbonyl)benzenesulfonohydrazide (CAS 866137-85-1)
- 3-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-tosyl-1H-pyrazole (CAS 477712-64-4)
Recommended Standards
- ((Propane-2,2-diylbis(4,1-phenylene))bis(oxy))bis(tert-butyldimethylsilane) (CAS 111983-38-1)
- N1,N2-didodecylethanebis(thioamide) (CAS 120-88-7)
- Cholesteryl isoamyl ether (CAS 74996-30-8)
- 5-Bromo-4-chloro-3-indolyl myristate (CAS 341972-95-0)
- tert-Butyl (2,6-dichloro-3-nitropyridin-4-yl)carbamate (CAS 1313726-52-1)
- N-(9-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide (CAS 51549-40-7)
- Tert-butyl 4-(5-(hydroxymethyl)-4-methylthiazol-2-yl)piperidine-1-carboxylate (CAS 857283-66-0)
- Benzyl (4-methylpiperidin-4-yl)carbamate (CAS 236406-15-8)
- 2,6-Dichloroimidazo[1,2-b]pyridazine (CAS 112581-77-8)
- Tert-butyl indoline-2-carboxylate (CAS 1218501-71-3)
- Methyl 1,2,3,4-tetrahydropyrido[1,2-a]benzimidazole-7-carboxylate (CAS 697234-09-6)
- (9R)-9-Aminocinchonan-6'-ol (CAS 960050-60-6)
- 2-Amino-5-(trifluoromethyl)thiazole-4-carboxylic acid (CAS 1086380-23-5)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
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