2-(Dimethylsulfamoyl)benzene-1-sulfonyl chloride CAS 103008-52-2
| CAS No. | 103008-52-2 |
| Molecular Formula | C8H10ClNO4S2 |
| Molecular Weight | 283.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Dimethylsulfamoyl)benzene-1-sulfonyl chloride.
2-(Dimethylsulfamoyl)benzene-1-sulfonyl chloride (CAS 103008-52-2) is a high-purity analytical reference standard with the molecular formula C8H10ClNO4S2 and a molecular weight of 283.75 g/mol.
Structurally, 2-(Dimethylsulfamoyl)benzene-1-sulfonyl chloride (C8H10ClNO4S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 283.75 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNO4S2 |
| Molecular Weight | 283.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Dimethylsulfamoyl Standards
- 3-(Dimethylsulfamoyl)benzene-1-sulfonyl chloride (CAS 197891-83-1)
- 4-(Dimethylsulfamoyl)benzene-1-sulfonyl chloride (CAS 677782-39-7)
- 1-Dimethylsulfamoyl-3-(trifluoromethyl)pyrazole-5-boronic acid (CAS 2377608-07-4)
- 2-[(dimethylsulfamoyl)amino]-3-(4-hydroxyphenyl)propanoic acid (CAS 1396965-69-7)
- 5-(Dimethylsulfamoyl)-2-[(2-hydroxyethyl)amino]benzoic acid (CAS 91431-32-2)
- [1-(dimethylsulfamoyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]boronic acid (CAS 917900-37-9)
- 2-[5-(dimethylsulfamoyl)-2-methoxyphenyl]acetic acid (CAS 926249-45-8)
- (6-Dimethylsulfamoyl-3-oxo-1,3-dihydro-isobenzofuran-1-yl)-acetic acid (CAS 144402-61-9)
Recommended Standards
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- 1-(3-(Ethylthio)pyridin-2-yl)ethan-1-one (CAS 1799326-03-6)
- Diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicarboxylate (CAS 2199-60-2)
- tert-Butyl (R)-3-([1,1'-biphenyl]-3-ylmethyl)piperazine-1-carboxylate (CAS 1260614-26-3)
- 4-Bromo-1-(2-fluoroethyl)-1H-pyrazole-5-carboxylic acid (CAS 1429419-24-8)
- 2-(3-(4-Methylpiperidin-1-yl)-3-oxopropyl)phenylboronic acid (CAS 1704063-65-9)
- 4-(1H-1,3-Benzimidazol-1-yl)benzenecarbaldehyde 4-(1H-benzo[d]imidazol-1-yl)benzaldehyde 90514-72-0 (CAS 90514-72-0)
- [1-(6-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester (CAS 1261233-51-5)
- 5-[3-(Trifluoromethyl)phenyl]-2,4(1H,3H)-pyrimidinedione (CAS 893737-25-2)
- o-Methoxycinnamylalcohol (CAS 1504-61-6)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
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