Rizatriptan impurity 01 CAS 1030849-63-8
| CAS No. | 1030849-63-8 |
| Molecular Formula | C16H22N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rizatriptan impurity 01 (CAS 1030849-63-8) is a certified pharmaceutical impurity reference standard with the molecular formula C16H22N5I and a molecular weight of 411.29 g/mol.
Rizatriptan impurity 01 (C16H22N5I) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H22N5 I |
| Molecular Weight | 411.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 5 |
Related Rizatriptan Standards
- Rizatriptan EP Impurity G (CAS 1000673-59-5)
- Rizatriptan Dimer Impurity 3 (CAS 1016900-25-6)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan Impurity 14 (CAS 110-95-2)
- Rizatriptan Impurity 4 (CAS 1135479-41-2)
- Rizatriptan Dimer (CAS 1135479-44-5)
- Rizatriptan Impurity 15 (CAS 114094-45-0)
- Rizatriptan Impurity 12 (CAS 119192-09-5)
Recommended Standards
- Domperidone Impurity 26 (CAS CATO-C4X-142026)
- Fluticasone Impurity N3 (CAS 398454-98-3)
- Memantine Impurity 66 (CAS CATO-C4X-105866)
- 3-(2-Fluorophenyl)-N-((2-methoxyadamantan-2-yl)methyl)propanamide (CAS 1798039-74-3)
- 1-(tert-Butylamino)anthracene-9,10-dione (CAS 65270-01-1)
- Methyl 4-amino-2-nitrobenzoate (CAS 84228-45-5)
- 4-Methylnaphthalen-2-amine (CAS 4523-46-0)
- 1'-(2-Methoxyethyl)-4',5'-dimethyl-3'-(phenylsulfonyl)-1'H-1,2'-bipyrrole (CAS 860648-74-4)
- Potassium 4-(4-Boc-piperazinomethyl)phenyltrifluoroborate (CAS 24203-36-9)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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