Rizatriptan EP Impurity G CAS 1000673-59-5
| CAS No. | 1000673-59-5 |
| Molecular Formula | C13H13ClN4 |
| Molecular Weight | 260.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 260.72 g/mol gives Rizatriptan EP Impurity G distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Rizatriptan EP Impurity G (CAS 1000673-59-5, C13H13ClN4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Rizatriptan EP Impurity G (C13H13ClN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 260.72 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H13ClN4 |
| Molecular Weight | 260.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Rizatriptan Standards
- Rizatriptan Impurity 6 (CAS 177270-91-6)
- Rizatriptan EP Impurity I (CAS 144034-84-4)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan - API Standards (CAS 144034-80-0)
- Rizatriptan EP Impurity C (CAS 208941-96-2)
- Rizatriptan Impurity 14 (CAS 4454-01-7)
- Rizatriptan-D6 (CAS 606927-07-5)
- Rizatriptan EP Impurity F (CAS 160194-39-8)
Recommended Standards
- Dapagliflozin Impurity 93 (CAS 525561-43-7)
- Phenacetin Impurity 8 (CAS 188905-67-1)
- tert-butyl 5-chlorocarbonyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate (CAS 2231279-02-8)
- Darolutamide Impurity 22 (CAS CATO-C4X-310622)
- Ertapenem Impurity 55 (CAS CATO-C4X-163355)
- Dapagliflozin Impurity 210 (CAS CATO-C4X-1138210)
- Argatroban Impurity 63 (CAS CATO-C4X-100763)
- 4-(3-Methylphenyl)-1-butene (CAS 92367-45-8)
- 4-Cyano-2-difluoromethoxy-3-methylbenzoic acid (CAS 1807287-35-9)
- (3-Bromophenyl)(4-pentylphenyl)methanone (CAS 951887-51-7)
- 3-(3-Amino-4-methoxyphenyl)propanoic acid (CAS 859189-60-9)
- 2-(2-Bromo-1H-benzo[d]imidazol-5-yl)acetic acid (CAS 1803895-92-2)
- 4-(Aminomethyl)-1,2-dihydropyrimidin-2-one (CAS 1330754-08-9)
- Semaglutide238 (CAS CATO-C4X-2226238)
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