5-Amino-1-(4-chloro-3-methoxyphenyl)-N-isopropyl-1H-1,2,3-triazole-4-carboxamide CAS 1032229-28-9
| CAS No. | 1032229-28-9 |
| Molecular Formula | C13H16ClN5O2 |
| Molecular Weight | 309.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-1-(4-chloro-3-methoxyphenyl)-N-isopropyl-1H-1,2,3-triazole-4-carboxamide.
5-Amino-1-(4-chloro-3-methoxyphenyl)-N-isopropyl-1H-1,2,3-triazole-4-carboxamide (CAS 1032229-28-9), molecular formula C13H16ClN5O2 and molecular weight 309.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Amino-1-(4-chloro-3-methoxyphenyl)-N-isopropyl-1H-1,2,3-triazole-4-carboxamide (C13H16ClN5O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Amino-1-(4-chloro-3-methoxyphenyl)-N-isopropyl-1H-1,2,3-triazole-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16ClN5O2 |
| Molecular Weight | 309.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
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- Mometasone Impurity 37 (CAS CATO-C4X-170437)
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- 2-(2-Ethyl-4-fluoro-1h-benzo[d]imidazol-1-yl)acetic acid (CAS 1781187-01-6)
- (1R,3S)-3-methoxycyclohexanamine;hydrochloride (CAS 2331211-70-0)
- Brl44385 (CAS 114778-60-8)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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